Stress-induced perinatal and transgenerational epigenetic programming of brain development and mental health
Research efforts during the past decades have provided intriguing evidence suggesting that
stressful experiences during pregnancy exert long-term consequences on the future mental …
stressful experiences during pregnancy exert long-term consequences on the future mental …
Immune cells-derived exosomes function as a double-edged sword: role in disease progression and their therapeutic applications
Exosomes, ranging in size from 30 to 150 nm as identified initially via electron microscopy in
1946, are one of the extracellular vesicles (EVs) produced by many cells and have been the …
1946, are one of the extracellular vesicles (EVs) produced by many cells and have been the …
An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex
The major cell classes of the brain differ in their developmental processes, metabolism,
signaling, and function. To better understand the functions and interactions of the cell types …
signaling, and function. To better understand the functions and interactions of the cell types …
Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells
M Chekulaeva, W Filipowicz - Current opinion in cell biology, 2009 - Elsevier
MicroRNAs (miRNAs) are 20-nt-long to 24-nt-long noncoding RNAs acting as post-
transcriptional regulators of gene expression in animals and plants. In mammals, more than …
transcriptional regulators of gene expression in animals and plants. In mammals, more than …
CARL lncRNA inhibits anoxia-induced mitochondrial fission and apoptosis in cardiomyocytes by impairing miR-539-dependent PHB2 downregulation
K Wang, BO Long, LY Zhou, F Liu, QY Zhou… - Nature …, 2014 - nature.com
Abnormal mitochondrial fission participates in the pathogenesis of many diseases. Long non-
coding RNAs (lncRNAs) are emerging as new players in gene regulation, but how lncRNAs …
coding RNAs (lncRNAs) are emerging as new players in gene regulation, but how lncRNAs …
Alteration of the micro RNA network during the progression of Alzheimer's disease
An overview of miRNAs altered in Alzheimer's disease (AD) was established by profiling the
hippocampus of a cohort of 41 late‐onset AD (LOAD) patients and 23 controls, showing …
hippocampus of a cohort of 41 late‐onset AD (LOAD) patients and 23 controls, showing …
Molecular control of oligodendrocyte development
Myelin is a multilayer lipid membrane structure that wraps and insulates axons, allowing for
the efficient propagation of action potentials. During developmental myelination of the …
the efficient propagation of action potentials. During developmental myelination of the …
Circular RNA mediates cardiomyocyte death via miRNA-dependent upregulation of MTP18 expression
K Wang, TY Gan, N Li, CY Liu, LY Zhou… - Cell Death & …, 2017 - nature.com
Circular RNAs (circRNAs) have important roles in several cellular processes. No study has
established the pathophysiological role for circRNAs in the heart. Here, we show that a …
established the pathophysiological role for circRNAs in the heart. Here, we show that a …
Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination
JC Dugas, TL Cuellar, A Scholze, B Ason, A Ibrahim… - Neuron, 2010 - cell.com
To investigate the role of microRNAs in regulating oligodendrocyte (OL) differentiation and
myelination, we utilized transgenic mice in which microRNA processing was disrupted in OL …
myelination, we utilized transgenic mice in which microRNA processing was disrupted in OL …
[HTML][HTML] MicroRNA-mediated control of oligodendrocyte differentiation
MicroRNAs (miRNAs) regulate various biological processes, but evidence for miRNAs that
control the differentiation program of specific neural cell types has been elusive. To …
control the differentiation program of specific neural cell types has been elusive. To …