Revolutionizing cancer therapy: nanoformulation of miRNA-34–enhancing delivery and efficacy for various cancer immunotherapies: a review

MP Fawzy, HAFM Hassan, NK Sedky, MS Nafie… - Nanoscale …, 2024 - pubs.rsc.org
Despite recent advancements in cancer therapies, challenges such as severe toxic effects,
non-selective targeting, resistance to chemotherapy and radiotherapy, and recurrence of …

Liposomal Formulations of Metallodrugs for Cancer Therapy

E Botter, I Caligiuri, F Rizzolio… - … Journal of Molecular …, 2024 - pmc.ncbi.nlm.nih.gov
The search for new antineoplastic agents is imperative, as cancer remains one of the most
preeminent causes of death worldwide. Since the discovery of the therapeutic potential of …

[HTML][HTML] Synergistic Enhancement of Carboplatin Efficacy through pH-Sensitive Nanoparticles Formulated Using Naturally Derived Boswellia Extract for Colorectal …

SA Fahmy, NK Sedky, HAFM Hassan, NM Abdel-Kader… - Pharmaceutics, 2024 - mdpi.com
Carboplatin (Cp) is a potent chemotherapeutic agent, but its effectiveness is constrained by
its associated side effects. Frankincense, an oleo-gum resin from the Boswellia sacra tree …

Facile sonochemically-assisted bioengineering of titanium dioxide nanoparticles and deciphering their potential in treating breast and lung cancers: biological …

NK Sedky, NK Mahdy, NM Abdel-Kader… - RSC …, 2024 - pubs.rsc.org
Combining sonochemistry with phytochemistry is a modern trend in the biosynthesis of
metallic nanoparticles (NPs), which contributes to the sustainability of chemical processes …

Formulation and optimization of surfactant-modified chitosan nanoparticles loaded with cefdinir for novel topical drug delivery: Elevating wound healing efficacy with …

MA Badie, MH Teaima, MA El-Nabarawi… - International Journal of …, 2024 - Elsevier
Burn wounds remain a significant global health concern, frequently exacerbated by bacterial
infections that hinder healing and raise morbidity rates. Cefdinir, a third-generation …

(Nano) biotechnological approaches in the treatment of cervical cancer: integration of engineering and biology

W **e, Z Xu - Frontiers in immunology, 2024 - frontiersin.org
Cervical cancer is one of the most malignant gynaecological tumors characterised with the
aggressive behaviour of the tumor cells. In spite of the development of different strategies for …

PEGylated Chitosan Nanoparticles Loaded with Betaine and Nedaplatin Hamper Breast Cancer: In Vitro and In Vivo Studies

SA Fahmy, A Ramzy, NM El Samaloty, NK Sedky… - ACS …, 2023 - ACS Publications
The current study investigates the anticancer effects of PEGylated chitosan nanoparticles
(CS NPs) coloaded with betaine (BT) and nedaplatin (ND) on breast adenocarcinoma (MCF …

[HTML][HTML] Sustainable Nanomedicine: Enhancement of Asplatin's Cytotoxicity In Vitro and In Vivo Using Green-Synthesized Zinc Oxide Nanoparticles Formed via …

HAFM Hassan, NK Sedky, MS Nafie, NK Mahdy… - Molecules, 2024 - mdpi.com
Chemoresistance encountered using conventional chemotherapy demands novel treatment
approaches. Asplatin (Asp), a novel platinum (IV) prodrug designed to release cisplatin and …

Recent Innovations of Mesoporous Silica Nanoparticles Combined with Photodynamic Therapy for Improving Cancer Treatment

DS Nady, A Hassan, MU Amin, U Bakowsky, SA Fahmy - Pharmaceutics, 2023 - mdpi.com
Cancer is a global health burden and is one of the leading causes of death. Photodynamic
therapy (PDT) is considered an alternative approach to conventional cancer treatment. PDT …

Box-Behnken design assisted approach in optimizing lipid composition for cationic liposome formulation as gene carrier

DR Setyawati, K Azzahra, E Mardliyati… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Background Cationic liposomes represent a promising non-viral carrier platform for gene
delivery. The successful intracellular delivery of genes to the target cell is highly influenced …