Bevacizumab-induced hypertension: Clinical presentation and molecular understanding

M Li, DL Kroetz - Pharmacology & therapeutics, 2018 - Elsevier
Bevacizumab is a vascular endothelial growth factor-A-specific angiogenesis inhibitor
indicated as an adjunct to chemotherapy for the treatment of several types of cancer …

Radiation pneumonitis and fibrosis: mechanisms underlying its pathogenesis and implications for future research

PG Tsoutsou, MI Koukourakis - International Journal of Radiation Oncology …, 2006 - Elsevier
Radiation pneumonitis and subsequent radiation pulmonary fibrosis are the two main dose-
limiting factors when irradiating the thorax that can have severe implications for patients' …

Angiogenesis in non-small cell lung cancer: the prognostic impact of neoangiogenesis and the cytokines VEGF and bFGF in tumours and blood

RM Bremnes, C Camps, R Sirera - Lung cancer, 2006 - Elsevier
BACKGROUND: Due to a dismal prognosis of advanced lung cancer, novel screening tools
and more effective treatments are clearly needed. Lately, an increasing number of tumour …

New insights for gynecological cancer therapies: from molecular mechanisms and clinical evidence to future directions

C Zhang, Y Sheng, X Sun, Y Wang - Cancer and Metastasis Reviews, 2023 - Springer
Advanced and recurrent gynecological cancers lack effective treatment and have poor
prognosis. Besides, there is urgent need for conservative treatment for fertility protection of …

VEGF and VEGFR genoty** in the prediction of clinical outcome for HCC patients receiving sorafenib: The ALICE‐1 study

M Scartozzi, L Faloppi… - … journal of cancer, 2014 - Wiley Online Library
Although new treatment modalities changed the global approach to hepatocellular
carcinoma (HCC), this disease still represents a medical challenge. Currently, the …

Ganoderma lucidum polysaccharides peptide inhibits the growth of vascular endothelial cell and the induction of VEGF in human lung cancer cell

Q Cao, ZB Lin - Life sciences, 2006 - Elsevier
Ganoderma lucidum Polysaccharide Peptide (Gl-PP) has shown some effects as anti-tumors
in mice and potential anti-angiogenesis. In this study, we elucidated the possible …

The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors

L Jain, CA Vargo, R Danesi, TM Sissung… - Molecular cancer …, 2009 - aacrjournals.org
Angiogenesis is crucial for development and metastasis of tumors, and vascular endothelial
growth factor (VEGF) is a key mediator of this process. The importance of VEGF in …

Pazopanib efficacy in renal cell carcinoma: evidence for predictive genetic markers in angiogenesis-related and exposure-related genes

CF Xu, NX Bing, HA Ball, D Rajagopalan… - Journal of clinical …, 2011 - ascopubs.org
Purpose Pazopanib, an oral angiogenesis inhibitor, is approved for the treatment of
advanced renal cell carcinoma (RCC). Response to pazopanib monotherapy varies …

Ganoderma: insights into anticancer effects

NV Kladar, NS Gavarić, BN Božin - European Journal of Cancer …, 2016 - journals.lww.com
The genus Ganoderma includes about 80 species growing on cut or rotten trees. The most
commonly used species is Ganoderma ludicum. Biomolecules responsible for the health …

Polymorphisms in the vascular endothelial growth factor gene and breast cancer in the Cancer Prevention Study II cohort

EJ Jacobs, HS Feigelson, EB Bain, KA Brady… - Breast Cancer …, 2006 - Springer
Introduction Vascular endothelial growth factor (VEGF) plays a central role in promoting
angiogenesis and is over-expressed in breast cancer. At least four polymorphisms in the …