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A minireview on N-acetylcysteine: an old drug with new approaches
IE Dhouib, M Jallouli, A Annabi, N Gharbi, S Elfazaa… - Life sciences, 2016 - Elsevier
Abstract N-acetylcysteine (NAC), a cysteine pro-drug and glutathione precursor has been
used in therapeutic practices for several decades, as a mucolytic agent and for the treatment …
used in therapeutic practices for several decades, as a mucolytic agent and for the treatment …
Biomarkers of mercury toxicity: Past, present, and future trends
Mercury (Hg) toxicity continues to represent a global health concern. Given that human
populations are mostly exposed to low chronic levels of mercurial compounds …
populations are mostly exposed to low chronic levels of mercurial compounds …
In vitro antioxidant activity of thiazolidinone derivatives of 1, 3-thiazole and 1, 3, 4-thiadiazole
M Djukic, M Fesatidou, I Xenikakis, A Geronikaki… - Chemico-biological …, 2018 - Elsevier
The initial steps in preclinical drug develo** research concern the synthesis of new
compounds for specific therapeutic use which needs to be confirmed by in vitro and then in …
compounds for specific therapeutic use which needs to be confirmed by in vitro and then in …
Cellular and molecular events leading to paraquat-induced apoptosis: mechanistic insights into Parkinson's disease pathophysiology
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the
cardinal features of tremor, bradykinesia, rigidity, and postural instability, in addition to other …
cardinal features of tremor, bradykinesia, rigidity, and postural instability, in addition to other …
Alterations in energy/redox metabolism induced by mitochondrial and environmental toxins: a specific role for glucose-6-phosphate-dehydrogenase and the pentose …
S Lei, L Zavala-Flores, A Garcia-Garcia… - ACS chemical …, 2014 - ACS Publications
Parkinson's disease (PD) is a multifactorial disorder with a complex etiology including
genetic risk factors, environmental exposures, and aging. While energy failure and oxidative …
genetic risk factors, environmental exposures, and aging. While energy failure and oxidative …
Carvedilol attenuates paraquat-induced lung injury by inhibition of proinflammatory cytokines, chemokine MCP-1, NF-κB activation and oxidative stress mediators
K Amirshahrokhi, AR Khalili - Cytokine, 2016 - Elsevier
Paraquat is a highly toxic herbicide that selectively accumulates in the lungs and causes
pulmonary damage through the oxidative and inflammatory processes. Carvedilol is a …
pulmonary damage through the oxidative and inflammatory processes. Carvedilol is a …
Protective effects of exogenous β-hydroxybutyrate on paraquat toxicity in rat kidney
T Wei, W Tian, F Liu, G **e - Biochemical and biophysical research …, 2014 - Elsevier
In this study, we demonstrated the protective effects of β-hydroxybutyrate (β-HB) against
paraquat (PQ)-induced kidney injury and elucidated the underlying molecular mechanisms …
paraquat (PQ)-induced kidney injury and elucidated the underlying molecular mechanisms …
Chlorogenic acid protective effects on paraquat‐induced pulmonary oxidative damage and fibrosis in rats
A Larki‐Harchegani, F Fayazbakhsh… - … of Biochemical and …, 2023 - Wiley Online Library
Paraquat (PQ) is a widely used herbicide that can cause severe oxidative and fibrotic
injuries in lung tissue. Due to the antioxidant and anti‐inflammatory properties of …
injuries in lung tissue. Due to the antioxidant and anti‐inflammatory properties of …
Paraquat and Parkinson's disease: The molecular crosstalk of upstream signal transduction pathways leading to apoptosis
Parkinson's disease (PD) is a heterogeneous disease involving a complex interaction
between genes and the environment that affects various cellular pathways and neural …
between genes and the environment that affects various cellular pathways and neural …
Oxidative stress, bioelements and androgen status in testes of rats subacutely exposed to cadmium
The objective of our study was to examine testicular toxicity of cadmium (Cd), focusing on
oxidative stress (OS), essential metals and androgenic status and morphological changes …
oxidative stress (OS), essential metals and androgenic status and morphological changes …