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Functionalized nanomaterials capable of crossing the blood–brain barrier
The blood–brain barrier (BBB) is a specialized semipermeable structure that highly
regulates exchanges between the central nervous system parenchyma and blood vessels …
regulates exchanges between the central nervous system parenchyma and blood vessels …
Chemical and biophysical signatures of the protein corona in nanomedicine
An inconvenient hurdle in the practice of nanomedicine is the protein corona, a spontaneous
collection of biomolecular species by nanoparticles in living systems. The protein corona is …
collection of biomolecular species by nanoparticles in living systems. The protein corona is …
[HTML][HTML] A historical review of brain drug delivery
The history of brain drug delivery is reviewed beginning with the first demonstration, in 1914,
that a drug for syphilis, salvarsan, did not enter the brain, due to the presence of a blood …
that a drug for syphilis, salvarsan, did not enter the brain, due to the presence of a blood …
The effects of protein corona on in vivo fate of nanocarriers
With the emerging advances in utilizing nanocarriers for biomedical applications, a
molecular-level understanding of the in vivo fate of nanocarriers is necessary. After …
molecular-level understanding of the in vivo fate of nanocarriers is necessary. After …
[HTML][HTML] Current research trends of nanomedicines
Owing to the inherent shortcomings of traditional therapeutic drugs in terms of inadequate
therapeutic efficacy and toxicity in clinical treatment, nanomedicine designs have received …
therapeutic efficacy and toxicity in clinical treatment, nanomedicine designs have received …
Protein corona: Friend or foe? Co-opting serum proteins for nanoparticle delivery
For systemically delivered nanoparticles to reach target tissues, they must first circulate long
enough to reach the target and extravasate there. A challenge is that the particles end up …
enough to reach the target and extravasate there. A challenge is that the particles end up …
Nanomedicine for diagnosis and treatment of atherosclerosis
With the changing disease spectrum, atherosclerosis has become increasingly prevalent
worldwide and the associated diseases have emerged as the leading cause of death. Due …
worldwide and the associated diseases have emerged as the leading cause of death. Due …
Receptor ligand-free mesoporous silica nanoparticles: a streamlined strategy for targeted drug delivery across the blood–brain barrier
Mesoporous silica nanoparticles (MSNs) represent a promising avenue for targeted brain
tumor therapy. However, the blood–brain barrier (BBB) often presents a formidable obstacle …
tumor therapy. However, the blood–brain barrier (BBB) often presents a formidable obstacle …
A detailed insight of the tumor targeting using nanocarrier drug delivery system
Human struggle against the deadly disease conditions is continued since ages. The
contribution of science and technology in fighting against these diseases cannot be ignored …
contribution of science and technology in fighting against these diseases cannot be ignored …
The therapeutic potential and clinical significance of exosomes as carriers of drug delivery system
T Li, X Li, G Han, M Liang, Z Yang, C Zhang, S Huang… - Pharmaceutics, 2022 - mdpi.com
Drug delivery system (DDS) realizes the drug delivery process through the drug carrier. As
an important part of DDS, the selection of the drug carrier material is extremely critical, which …
an important part of DDS, the selection of the drug carrier material is extremely critical, which …