Proteostasis in Parkinson's disease: Recent development and possible implication in diagnosis and therapeutics

A Kulkarni, K Preeti, KP Tryphena, S Srivastava… - Ageing Research …, 2023 - Elsevier
The protein dyshomeostasis is identified as the hallmark of many age-related
neurodegenerative disorders including Parkinson's disease (PD). The diseased brain shows …

Integration of miRNA's theranostic potential with nanotechnology: promises and challenges for Parkinson's disease therapeutics

KP Tryphena, G Singh, N Jain, P Famta… - Mechanisms of Ageing …, 2023 - Elsevier
Despite the wide research going on in Parkinson's disease (PD), the burden of PD still
remains high and continues to increase. The current drugs available for the treatment of PD …

The role of non-coding RNAs in the pathogenesis of Parkinson's disease: recent advancement

H Zhang, L Yao, Z Zheng, S Koc, G Lu - Pharmaceuticals, 2022 - mdpi.com
Parkinson's disease (PD) is a prevalent neurodegenerative aging disorder that manifests as
motor and non-motor symptoms, and its etiopathogenesis is influenced by non-coding RNAs …

Dysregulated miRNAs as biomarkers and therapeutical targets in neurodegenerative diseases

G Gentile, G Morello, V La Cognata… - Journal of Personalized …, 2022 - mdpi.com
Alzheimer's disease (AD), Parkinson's disease (PD), and Amyotrophic Lateral Sclerosis
(ALS) are representative neurodegenerative diseases (NDs) characterized by degeneration …

[HTML][HTML] Advances in the synthesis and physiological metabolic regulation of nicotinamide mononucleotide

C Zheng, Y Li, X Wu, L Gao, X Chen - Nutrients, 2024 - mdpi.com
Nicotinamide mononucleotide (NMN), the direct precursor of nicotinamide adenine
dinucleotide (NAD+), is involved in the regulation of many physiological and metabolic …

[HTML][HTML] Parkinson's disease: biomarkers for diagnosis and disease progression

R Arya, AKMA Haque, H Shakya… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Parkinson's disease (PD) is a progressive neurological disease that causes both motor and
nonmotor symptoms. While our understanding of putative mechanisms has advanced …

Common microRNA regulated pathways in Alzheimer's and Parkinson's disease

B Awuson-David, AC Williams, B Wright… - Frontiers in …, 2023 - frontiersin.org
MicroRNAs (miRNAs) are small non-coding RNAs involved in gene regulation. Recently,
miRNA dysregulation has been found in neurodegenerative diseases such as Alzheimer's …

Promising biomarkers and therapeutic targets for the management of Parkinson's disease: recent advancements and contemporary research

MA Khan, N Haider, T Singh, R Bandopadhyay… - Metabolic Brain …, 2023 - Springer
Parkinson's disease (PD) is one of the progressive neurological diseases which affect
around 10 million population worldwide. The clinical manifestation of motor symptoms in PD …

[HTML][HTML] Biomarkers in Parkinson's disease: A state of the art review

KY Yamashita, S Bhoopatiraju, BD Silverglate… - Biomarkers in …, 2023 - Elsevier
Biomarkers in Parkinson's disease are widely researched in the field of neuropsychiatry.
Though Parkinson's disease is diagnosed clinically, biomarkers prove to be a promising …

Shared miRNA landscapes of COVID-19 and neurodegeneration confirm neuroinflammation as an important overlap** feature

S Redenšek Trampuž, D Vogrinc, K Goričar… - Frontiers in molecular …, 2023 - frontiersin.org
Introduction Development and worsening of most common neurodegenerative diseases,
such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis, have been …