Ultrasound-targeted microbubble destruction remodels tumour microenvironment to improve immunotherapeutic effect

S Liu, Y Zhang, Y Liu, W Wang, S Gao, W Yuan… - British Journal of …, 2023‏ - nature.com
Cancer immunotherapy (CIT) has gained increasing attention and made promising progress
in recent years, especially immune checkpoint inhibitors such as antibodies blocking …

Targeted microbubbles for drug, gene, and cell delivery in therapy and immunotherapy

JA Navarro-Becerra, MA Borden - Pharmaceutics, 2023‏ - mdpi.com
Microbubbles are 1–10 μm diameter gas-filled acoustically-active particles, typically
stabilized by a phospholipid monolayer shell. Microbubbles can be engineered through …

[HTML][HTML] Tracking adoptive natural killer cells via ultrasound imaging assisted with nanobubbles

Y Jiang, X Hou, X Zhao, J **g, L Sun - Acta biomaterialia, 2023‏ - Elsevier
The recent years has witnessed an exponential growth in the field of natural killer (NK) cell-
based immunotherapy for cancer treatment. As a prerequisite to precise evaluations and on …

[HTML][HTML] Acoustically driven cell-based microrobots for targeted tumor therapy

HX Cao, VD Nguyen, D Jung, E Choi, CS Kim, JO Park… - Pharmaceutics, 2022‏ - mdpi.com
Targeted drug delivery using microrobots manipulated by an external actuator has
significant potential to be a practical approach for wireless delivery of therapeutic agents to …

Targeted Drug Delivery: From Chemistry to Robotics at Small Scales

M Kim, JD Nicholas, J Puigmartí-Luis… - Annual Review of …, 2024‏ - annualreviews.org
The limited bioavailability, susceptibility to degradation, and adverse side effects of novel
drugs often hinder their effective administration. Nanoparticles, with customizable properties …

Applications and future prospects of micro/nanorobots utilizing diverse biological carriers

Y Lv, R Pu, Y Tao, X Yang, H Mu, H Wang, W Sun - Micromachines, 2023‏ - mdpi.com
Targeted drug delivery using micro-nano robots (MNRs) is a rapidly advancing and
promising field in biomedical research. MNRs enable precise delivery of drugs, addressing …

pH‐Sensitive Magnetic Nanoparticle‐Mediated Natural‐Killer‐Cell‐Based Microrobots for Dual‐Targeted Delivery and Induction of Pro‐Inflammatory Macrophage …

VD Nguyen, J Park, S Choi, KT Nguyen, H Kim… - Small …, 2024‏ - Wiley Online Library
Adoptive cell therapy using natural killer (NK) cells emerges as the next‐generation cancer
immunotherapy. Based on the intrinsic capability of direct cancer cell necrosis without prior …

Contrast agents for hepatocellular carcinoma imaging: value and progression

Y Zhang, K Numata, Y Du, S Maeda - Frontiers in Oncology, 2022‏ - frontiersin.org
Hepatocellular carcinoma (HCC) has the third-highest incidence in cancers and has
become one of the leading threats to cancer death. With the research on the etiological …

Focused ultrasound-mediated small-molecule delivery to potentiate immune checkpoint blockade in solid tumors

Q Wu, Y **a, X **ong, X Duan, X Pang… - Frontiers in …, 2023‏ - frontiersin.org
In the last decade, immune checkpoint blockade (ICB) has revolutionized the standard of
treatment for solid tumors. Despite success in several immunogenic tumor types evidenced …

[PDF][PDF] Acoustically Driven Cell-Based Microrobots for Targeted Tumor Therapy. Pharmaceutics 2022, 14, 2143

HX Cao, VD Nguyen, D Jung, E Choi, CS Kim, JO Park… - 2022‏ - academia.edu
Targeted drug delivery using microrobots manipulated by an external actuator has
significant potential to be a practical approach for wireless delivery of therapeutic agents to …