[HTML][HTML] Focus: skin: current developments in the immunology of psoriasis
F Grän, A Kerstan, E Serfling, M Goebeler… - The Yale journal of …, 2020 - ncbi.nlm.nih.gov
Psoriasis is a frequent inflammatory skin disease. Fundamental research on the
pathogenesis of psoriasis has substantially increased our understanding of skin …
pathogenesis of psoriasis has substantially increased our understanding of skin …
Advances in understanding the immunological pathways in psoriasis
Psoriasis vulgaris is a chronic, immune-mediated, inflammatory, polygenic skin disorder
affecting approximately 2% of the population. It has a great impact on quality of life; patients …
affecting approximately 2% of the population. It has a great impact on quality of life; patients …
[HTML][HTML] Crosstalk between keratinocytes and T cells in a 3D microenvironment: a model to study inflammatory skin diseases
EH Van Den Bogaard, GS Tjabringa, I Joosten… - Journal of Investigative …, 2014 - Elsevier
The interaction between keratinocytes and immune cells plays a major role in the
development of inflammatory skin diseases like psoriasis and atopic dermatitis …
development of inflammatory skin diseases like psoriasis and atopic dermatitis …
The roles of toll-like receptor 4, CD33, CD68, CD69, or CD147/EMMPRIN for monocyte activation by the DAMP S100A8/S100A9
A Möller, SL Jauch-Speer, S Gandhi, T Vogl… - Frontiers in …, 2023 - frontiersin.org
The S100A8/A9 heterocomplex is an abundant damage-associated molecular pattern and
mainly expressed by monocytes, inflammatory activated keratinocytes and neutrophilic …
mainly expressed by monocytes, inflammatory activated keratinocytes and neutrophilic …
The roles of T cells in psoriasis
P Zhang, Y Su, S Li, H Chen, R Wu, H Wu - Frontiers in Immunology, 2023 - frontiersin.org
Psoriasis is a recurring inflammatory skin condition characterized by scaly, red patches on
the skin. It affects approximately 3% of the US population and is associated with histological …
the skin. It affects approximately 3% of the US population and is associated with histological …
The role of p38 MAPK in the aetiopathogenesis of psoriasis and psoriatic arthritis
The pathogenetic mechanisms responsible for the induction of immune‐mediated disorders,
such as psoriasis, remain not well characterized. Molecular signaling pathways are not well …
such as psoriasis, remain not well characterized. Molecular signaling pathways are not well …
Discovery of selective inhibitors of endoplasmic reticulum aminopeptidase 1
ERAP1 is an endoplasmic reticulum-resident zinc aminopeptidase that plays an important
role in the immune system by trimming peptides for loading onto major histocompatibility …
role in the immune system by trimming peptides for loading onto major histocompatibility …
Foxp3+ T reg cells control psoriasiform inflammation by restraining an IFN-I–driven CD8+ T cell response
Psoriasis is a complex inflammatory skin disease affecting∼ 3% of the population
worldwide. Although type I interferons (IFN-I) are thought to be involved in its pathogenesis …
worldwide. Although type I interferons (IFN-I) are thought to be involved in its pathogenesis …
RNA-seq and flow-cytometry of conventional, scalp, and palmoplantar psoriasis reveal shared and distinct molecular pathways
R Ahn, D Yan, HW Chang, K Lee, S Bhattarai… - Scientific reports, 2018 - nature.com
It has long been recognized that anatomic location is an important feature for defining
distinct subtypes of plaque psoriasis. However, little is known about the molecular …
distinct subtypes of plaque psoriasis. However, little is known about the molecular …
[HTML][HTML] Involvement of the cytokine TWEAK in the pathogenesis of psoriasis vulgaris, pustular psoriasis, and erythrodermic psoriasis
Psoriasis is a common chronic inflammatory dermatitis in which various cytokines play a
detrimental role. The cytokine tumor necrosis factor-related weak inducer of apoptosis …
detrimental role. The cytokine tumor necrosis factor-related weak inducer of apoptosis …