MYC activation is a known hallmark of cancer as it governs the gene targets involved in
various facets of cancer progression. Of interest, MYC governs oncometabolism through the …

In recent years, the research community has, with comprehensive systems biology
approaches and related technologies, gained insight into the vast complexity of numerous …

Duchenne muscular dystrophy is a genetic disorder that shows chronic and progressive
damage to skeletal and cardiac muscle leading to premature death. Antiinflammatory …

Complementary assays are required to comprehensively map complex biological entities
such as genomes, proteomes and interactome networks. However, how various assays can …

Phosphatidylcholine transfer protein (PC-TP; synonym StarD2) is a soluble lipid-binding
protein that transports phosphatidylcholine (PC) between cellular membranes. To better …

Background YAP1 is a core protein of the Hippo signaling pathway and is associated with
malignancy and immunosuppression. In the present study, we discovered a novel lncRNA …

Comprehensive sequencing of patient tumors reveals genomic mutations across tumor
types that enable tumorigenesis and progression. A subset of oncogenic driver mutations …

Motivation As cancer genomics initiatives move toward comprehensive identification of
genetic alterations in cancer, attention is now turning to understanding how interactions …

PKR is a cellular kinase involved in the regulation of the integrative stress response (ISR)
and pro-inflammatory pathways. Two N-terminal dsRNA Binding Domains (DRBD) are …

Abstract Background African American women experience a twofold higher incidence of
triple-negative breast cancer (TNBC) and are 40% more likely to die from breast cancer than …