Exploring the mechanical perspective of a new anti-tumor agent: melatonin

S Rohilla, M Singh, S Priya, WH Almalki… - Journal of …, 2023 - dl.begellhouse.com
Melatonin is a serotonin-derived pineal gland hormone with many biological functions like
regulating the sleep-wake cycle, circadian rhythm, menstrual cycle, aging, immunity, and …

[HTML][HTML] Roles of mushroom polysaccharides in chronic disease management

S Zhang, LEI Lin, Z Yun, FY Ye, GH Zhao - Journal of Integrative …, 2022 - Elsevier
Chronic diseases have drawn much attention as the primary cause of death and disability. In
exploring novel side-effect-free agents against chronic diseases, significant efforts have …

Melatonin reduces proliferation and promotes apoptosis of bladder cancer cells by suppressing O‐GlcNAcylation of cyclin‐dependent‐like kinase 5

J Wu, Z Tan, H Li, M Lin, Y Jiang, L Liang… - Journal of Pineal …, 2021 - Wiley Online Library
Melatonin helps to maintain circadian rhythm, exerts anticancer activity, and plays key roles
in regulation of glucose homeostasis and energy metabolism. Glycosylation, a form of …

Effect of Apatinib plus melatonin on vasculogenic mimicry formation by cancer stem cells from breast cancer cell line

NF Maroufi, M Rashidi, V Vahedian, R Jahanbazi… - Breast Cancer, 2022 - Springer
Background and aim Vasculogenic mimicry (VM) is one of the most important causes of
breast cancer metastasis and resistance against drugs. The cancer stem cells (CSCs) are …

Melatonin effect on breast and ovarian cancers by targeting the PI3K/Akt/mTOR pathway

V Pourbarkhordar, S Rahmani, A Roohbakhsh… - IUBMB …, 2024 - Wiley Online Library
Melatonin, the hormone of the pineal gland, possesses a range of physiological functions,
and recently, its anticancer effect has become more apparent. A more thorough …

Melatonin receptors: A key mediator in animal reproduction

Y Gao, S Zhao, Y Zhang, Q Zhang - Veterinary Sciences, 2022 - mdpi.com
Simple Summary Animal reproduction is closely related to economic benefits and food
safety in domestic animals, as well as human fertility. There are many factors that affect the …

Melatonin enhances cell death and suppresses the metastatic capacity of ovarian cancer cells by attenuating the signaling of multiple kinases

MS Cucielo, PP Freire, MT Emílio-Silva… - … -Research and Practice, 2023 - Elsevier
Background Ovarian cancer is a highly aggressive disease that is frequently diagnosed in
advanced stages. Melatonin, with its numerous antitumor properties, holds great promise in …

Application value of circulating LncRNA in diagnosis, treatment, and prognosis of breast cancer

M Li, Y Zhao, H Li, X Deng, M Sheng - Functional & Integrative Genomics, 2023 - Springer
Breast cancer is the malignant tumor with the highest incidence in women worldwide. It is
highly heterogeneous, has a high incidence of drug resistance, recurrence, and metastasis …

The role of SOX family in cancer stem cell maintenance: With a focus on SOX2

F Pouremamali, V Vahedian, N Hassani… - … -Research and Practice, 2022 - Elsevier
The role of cancer stem cells (CSCs) in cancer incidence, drug resistance, and relapse after
chemotherapy has been discussed and it has been confirmed that CSCs are extremely …

Melatonin-mediated IGF-1/GLP-1 activation in experimental OCD rats: evidence from CSF, blood plasma, brain and in-silico investigations

A Giri, S Mehan, Z Khan, GD Gupta… - Biochemical pharmacology, 2023 - Elsevier
Obsessive-compulsive disorder (OCD) is a neuropsychiatric condition characterized by
intrusive, repetitive thoughts and behaviors. Our study uses a validated 8-OH-DPAT-induced …