Background: Orf is a highly contagious zoonosis caused by Orf virus (ORFV), which is
endemic in sheep and goats worldwide. Human Orf is usually a self-limiting disease, but …

Currently, for ovarian cancer, which has the highest mortality rate among all gynecological
cancers, the standard treatment protocol is initial tumor cytoreductive surgery followed by …

Background Ovarian adenocarcinoma (OVAD) frequently metastasizes to the peritoneal
cavity and manifests by the formation of ascites, which constitutes a tumor-promoting …

Every type of cancer tissue is theoretically more vulnerable to viral infection. This natural
proclivity has been harnessed as a new anti-cancer therapy by employing oncolytic viruses …

The ability to expand and activate natural Killer (NK) cells ex vivo has dramatically changed
the landscape in the development of novel adoptive cell therapies for treating cancer over …

Background Treatment of some blood cancers with T cells that express a chimeric antigen
receptor (CAR) against CD19 have shown remarkable results. In contrast, CAR-T cell …

Oncolytic virotherapy (OVT) has emerged as a promising cancer immunotherapy, and is
capable of potentiating other immunotherapies due to its capacity to increase tumor …

Background: Ovarian cancer (OC) has a high mortality rate and poses a severe threat to
women's health. However, abnormal gene expression underlying the tumorigenesis of OC …

Neutrophils are innate leukocytes with diverse effector functions that allow them to respond
to pathogens rapidly. Accumulating evidence has highlighted these cells' complex roles in …

Immunotherapies revive host immune responses against tumors by stimulating innate and
adaptive immune effector cells with anti-tumor functions. Thus, detailed studies of …