Type 2 immunity in the skin and lungs
CA Akdis, PD Arkwright, MC Brüggen, W Busse… - Allergy, 2020 - Wiley Online Library
There has been extensive progress in understanding the cellular and molecular
mechanisms of inflammation and immune regulation in allergic diseases of the skin and …
mechanisms of inflammation and immune regulation in allergic diseases of the skin and …
Understanding asthma phenotypes, endotypes, and mechanisms of disease
ME Kuruvilla, FEH Lee, GB Lee - Clinical reviews in allergy & immunology, 2019 - Springer
The model of asthma as a single entity has now been replaced by a much more complex
biological network of distinct and interrelating inflammatory pathways. The term asthma is …
biological network of distinct and interrelating inflammatory pathways. The term asthma is …
Heterogeneity of type 2 innate lymphoid cells
More than a decade ago, type 2 innate lymphoid cells (ILC2s) were discovered to be
members of a family of innate immune cells consisting of five subsets that form a first line of …
members of a family of innate immune cells consisting of five subsets that form a first line of …
Innate lymphoid cells in mucosal immunity
Innate lymphoid cells (ILCs) are innate counterparts of T cells that contribute to immune
responses by secreting effector cytokines and regulating the functions of other innate and …
responses by secreting effector cytokines and regulating the functions of other innate and …
Eosinophils from physiology to disease: a comprehensive review
Despite being the second least represented granulocyte subpopulation in the circulating
blood, eosinophils are receiving a growing interest from the scientific community, due to their …
blood, eosinophils are receiving a growing interest from the scientific community, due to their …
Thymic stromal lymphopoietin: its role and potential as a therapeutic target in asthma
Introduction Thymic stromal lymphopoietin (TSLP), an epithelial cytokine (alarmin), is a
central regulator of the immune response to inhaled environmental insults such as …
central regulator of the immune response to inhaled environmental insults such as …
Adult chronic rhinosinusitis
Chronic rhinosinusitis (CRS) occurs in> 10% of the adult population in Europe and the USA
and can be differentiated into CRS without nasal polyps and CRS with nasal polyps …
and can be differentiated into CRS without nasal polyps and CRS with nasal polyps …
New insights into the pathophysiology and therapeutic targets of asthma and comorbid chronic rhinosinusitis with or without nasal polyposis
Asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) or without (CRSsNP) are
chronic respiratory diseases. These two disorders often co-exist based on common …
chronic respiratory diseases. These two disorders often co-exist based on common …
Sounding the alarmins—the role of alarmin cytokines in asthma
The alarmin cytokines thymic stromal lymphopoietin (TSLP), interleukin (IL)‐33, and IL‐25
are epithelial cell‐derived mediators that contribute to the pathobiology and …
are epithelial cell‐derived mediators that contribute to the pathobiology and …
Group 2 innate lymphoid cells in airway diseases
A Kato - Chest, 2019 - Elsevier
Group 2 innate lymphoid cells (ILC2s) are increasingly recognized as a key controller of type
2 inflammation, and are well known to be highly elevated in human airway type 2 …
2 inflammation, and are well known to be highly elevated in human airway type 2 …