Biofilm formation in living organisms is associated to tissue and implant infections, and it has
also been linked to the contribution of antibiotic resistance. Thus, understanding biofilm …

Disruptions in the intestinal epithelial barrier can result in devastating consequences and a
multitude of disease syndromes, particularly among preterm neonates. The association …

Inflammatory bowel disease can be caused by the dysfunction of the intestinal mucosal
barrier and dysregulation of gut microbiota. Traditional treatments use drugs to manage …

Colon mucus segregates the intestinal microbiota from host tissues, but how it organizes to
function throughout the colon is unclear. In mice, we found that colon mucus consists of two …

Simple Summary We review the value of large animal models for improving the translation of
biomedical research for human application, focusing primarily on sheep. Abstract An …

Research on gut microbiota has generally focused on fecal samples, representing luminal
content of the large intestine. However, nutrient uptake is restricted to the small intestine …

Simple Summary The current review aimed to provide an overview on the problems
associated with weaning with a special focus on gut health, and also highlighted the …

A history of safe use is a backbone of safety assessments for many current probiotic species,
however, there is no global harmonization regarding requirements for establishing probiotic …

Background Large animal models, such as the dog, are increasingly being used for studying
diseases including gastrointestinal (GI) disorders. Dogs share similar environmental …

Microglia/macrophage mediated-inflammation, a main contributor to the microenvironment
after spinal cord injury (SCI), persists for a long period of time and affects SCI repair …