Regulation of immunity during visceral Leishmania infection

V Rodrigues, A Cordeiro-da-Silva, M Laforge… - Parasites & vectors, 2016 - Springer
Unicellular eukaryotes of the genus Leishmania are collectively responsible for a
heterogeneous group of diseases known as leishmaniasis. The visceral form of …

[HTML][HTML] From infection to death: an overview of the pathogenesis of visceral leishmaniasis

CHN Costa, KP Chang, DL Costa, FVM Cunha - Pathogens, 2023 - mdpi.com
Kala-azar, also known as visceral leishmaniasis (VL), is a disease caused by Leishmania
infantum and L. donovani. Patients experience symptoms such as fever, weight loss …

A third generation vaccine for human visceral leishmaniasis and post kala azar dermal leishmaniasis: First-in-human trial of ChAd63-KH

M Osman, A Mistry, A Keding, R Gabe… - PLoS neglected …, 2017 - journals.plos.org
Background Visceral leishmaniasis (VL or kala azar) is the most serious form of human
leishmaniasis, responsible for over 20,000 deaths annually, and post kala azar dermal …

Role of cytokines in experimental and human visceral leishmaniasis

M Samant, U Sahu, SC Pandey… - Frontiers in cellular and …, 2021 - frontiersin.org
Visceral Leishmaniasis (VL) is the most fatal form of disease leishmaniasis. To date, there
are no effective prophylactic measures and therapeutics available against VL. Recently, new …

Immune regulation during chronic visceral leishmaniasis

RJ Faleiro, R Kumar, LM Hafner… - PLoS neglected tropical …, 2014 - journals.plos.org
Visceral leishmaniasis is a chronic parasitic disease associated with severe immune
dysfunction. Treatment options are limited to relatively toxic drugs, and there is no vaccine …

Host–pathogen interaction in leishmaniasis: immune response and vaccination strategies

H Yasmin, A Adhikary, MN Al-Ahdal, S Roy, U Kishore - Immuno, 2022 - mdpi.com
Leishmaniasis is a zoonotic and vector-borne infectious disease that is caused by the genus
Leishmania belonging to the trypanosomatid family. The protozoan parasite has a digenetic …

Leishmania Hijacks Myeloid Cells for Immune Escape

M Martínez-López, M Soto, S Iborra… - Frontiers in …, 2018 - frontiersin.org
Protozoan parasites of the Leishmania genus are the causative agents of leishmaniasis, a
group of neglected tropical diseases whose clinical manifestations vary depending on the …

A primer on cytokines

P Chauhan, A Nair, A Patidar, J Dandapat, A Sarkar… - Cytokine, 2021 - Elsevier
Cytokines are pleiotropic polypeptides that control the development of and responses
mediated by immune cells. Cytokine classification predominantly relies on [1] the target …

Deception and Manipulation: The Arms of Leishmania, a Successful Parasite

P Cecílio, B Pérez-Cabezas, N Santarém… - Frontiers in …, 2014 - frontiersin.org
Leishmania spp. are intracellular parasitic protozoa responsible for a group of neglected
tropical diseases, endemic in 98 countries around the world, called leishmaniasis. These …

Leishmania Spp-Host Interaction: There Is Always an Onset, but Is There an End?

F Conceição-Silva, FN Morgado - Frontiers in cellular and infection …, 2019 - frontiersin.org
For a long time Leishmaniasis had been considered as a neglected tropical disease.
Recently, it has become a priority in public health all over the world for different aspects such …