Alcoholic liver disease (ALD) is a global public health challenge due to the high incidence
and lack of effective therapeutics. Evidence from animal studies and ALD patients has …

Ferroptosis is a novel mechanism of programmed cell death characterized by an iron
overload-induced lipid peroxidation cascade. The incidence of alcoholic liver disease (ALD) …

Understanding the role of iron in ethanol-derived hepatic stress could help elucidate the
efficacy of dietary or clinical interventions designed to minimize liver damage from chronic …

While past studies have provided evidence linking excessive alcohol consumption to
increased risk for cardiovascular diseases (CVDs) and colorectal cancer (CRC), existing …

AIM: To understand the role of toll-like receptor 4 (TLR4) signaling in the regulation of iron-
regulatory hormone, hepcidin by chronic alcohol consumption. METHODS: For chronic …

This study investigates the regulation of hepcidin, the key iron-regulatory molecule, by
alcohol and hydrogen peroxide (H2O2) in glutathione peroxidase-1 (gpx-1−/−) and catalase …

Purpose. We aim to figure out the effect of metallothioneins on iodide excess induced
oxidative stress in the thyroid. Methods. Eight‐week‐old MT‐I/II knockout (MT‐I/II KO) mice …

Iron-related disorders of the liver can result in serious health conditions, such as liver
cirrhosis. Evidence on the role of modifiable lifestyle factors like nutrition in liver iron storage …

Abstract Background & Aims There is clear evidence that lifestyle factors affect iron
bioavailability. However, information regarding the effect of alcohol and caffeine …

We used high-performance liquid chromatography to separate urine obtained from whole-
body gamma-irradiated mice (4 Gy) before analyzing each fraction with matrix-assisted laser …