Biobanking as a tool for genomic research: from allele frequencies to cross-ancestry association studies

TE Lazareva, YA Barbitoff, AI Changalidis… - Journal of Personalized …, 2022 - mdpi.com
In recent years, great advances have been made in the field of collection, storage, and
analysis of biological samples. Large collections of samples, biobanks, have been …

Integrative functional genomic analyses identify genetic variants influencing skin pigmentation in Africans

Y Feng, N ** of retinal vascular complexity loci identifies Notch regulation as a shared mechanism with myocardial infarction outcomes
A Villaplana-Velasco, M Pigeyre, J Engelmann… - Communications …, 2023 - nature.com
There is increasing evidence that the complexity of the retinal vasculature measured as
fractal dimension, Df, might offer earlier insights into the progression of coronary artery …

Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma

O Urtatiz, A Haage, G Tanentzapf, CD Van Raamsdonk - Elife, 2021 - elifesciences.org
Different melanoma subtypes exhibit specific and non-overlap** sets of oncogene and
tumor suppressor mutations, despite a common cell of origin in melanocytes. For example …

Validation of selection signatures for coat color in the Podolica Italiana gray cattle breed

S Bruno, G Rovelli, V Landi, F Sbarra, A Quaglia… - Frontiers in …, 2024 - frontiersin.org
Taurine and indicine gray cattle represent relevant livestock resources in many countries of
the world. A gray coat color and pigmented skin, which are common in most of the gray cattle …

Genome wide association study and meta‐analysis identified multiple new risk loci for freckles in 4813 Chinese individuals

S Luo, Z Li, M Wang, Z Liu, D Wang… - Pigment Cell & …, 2024 - Wiley Online Library
Freckle is a prevalent pigmentary dermatosis with an obvious hereditary component.
Dozens of freckles risk loci have been discovered through research on multiple traits or …