Advances and opportunities in the exciting world of azobenzenes

FA Jerca, VV Jerca, R Hoogenboom - Nature Reviews Chemistry, 2022 - nature.com
Azobenzenes are archetypal molecules that have a central role in fundamental and applied
research. Over the course of almost two centuries, the area of azobenzenes has witnessed …

Advances in application of azobenzene as a trigger in biomedicine: molecular design and spontaneous assembly

HB Cheng, S Zhang, J Qi, XJ Liang… - Advanced …, 2021 - Wiley Online Library
Azobenzene is a well‐known derivative of stimulus‐responsive molecular switches and has
shown superior performance as a functional material in biomedical applications. The results …

Fluorogenic probes for disease-relevant enzymes

J Zhang, X Chai, XP He, HJ Kim, J Yoon… - Chemical Society …, 2019 - pubs.rsc.org
Traditional biochemical methods for enzyme detection are mainly based on antibody-based
immunoassays, which lack the ability to monitor the spatiotemporal distribution and, in …

Azobenzene-based solar thermal fuels: design, properties, and applications

L Dong, Y Feng, L Wang, W Feng - Chemical Society Reviews, 2018 - pubs.rsc.org
Development of renewable energy technologies has been a significant area of research
amongst scientists with the aim of attaining a sustainable world society. Solar thermal fuels …

Photoresponsive molecular tools for emerging applications of light in medicine

IM Welleman, MWH Hoorens, BL Feringa… - Chemical …, 2020 - pubs.rsc.org
Light-based therapeutic and imaging modalities, which emerge in clinical applications, rely
on molecular tools, such as photocleavable protecting groups and photoswitches that …

Visible‐light‐activated molecular switches

D Bléger, S Hecht - Angewandte Chemie International Edition, 2015 - Wiley Online Library
The ability to influence key properties of molecular systems by using light holds much
promise for the fields of materials science and life sciences. The cornerstone of such …

PHOTACs enable optical control of protein degradation

M Reynders, BS Matsuura, M Bérouti, D Simoneschi… - Science …, 2020 - science.org
PROTACs (PROteolysis TArgeting Chimeras) are bifunctional molecules that target proteins
for ubiquitylation by an E3 ligase complex and subsequent degradation by the proteasome …

Red-shifting azobenzene photoswitches for in vivo use

M Dong, A Babalhavaeji, S Samanta… - Accounts of chemical …, 2015 - ACS Publications
Conspectus Recently, there has been a great deal of interest in using the
photoisomerization of azobenzene compounds to control specific biological targets in vivo …

Photopharmacology: beyond proof of principle

WA Velema, W Szymanski… - Journal of the American …, 2014 - ACS Publications
Pharmacotherapy is often severely hindered by issues related to poor drug selectivity,
including side effects, environmental toxicity, and the emergence of resistance. Lack of …

[HTML][HTML] Reversible photocontrol of biological systems by the incorporation of molecular photoswitches

W Szymanski, JM Beierle, HAV Kistemaker… - Chemical …, 2013 - ACS Publications
Controlling the conformation and activity of biomolecules in a reversible manner is a
fascinating challenge (1-3) that has an outstanding potential for the study of and interference …