Dexmedetomidine (DEX), a highly specific α2‑adrenergic agonist, which exhibits
anaesthetic‑sparing, analgesia and sympatholytic properties. DEX modulates gene …

What is known and objective Acute kidney injury (AKI) is a complication following surgery
and has been associated with worsened patient outcomes. Providers have used agents that …

Background The surgical stress response plays an important role on the pathogenesis of
perioperative cardiac complications. Alpha‐2 adrenergic agonists attenuate this response …

Dexmedetomidine (Dex) demonstrates sedative and analgesic effects. We investigated the
intraoperative and postoperative effects of intraoperative Dex administration during surgery …

Dexmedetomidine (DEX) is a highly selective and potent α2-adrenoceptor (α2-AR) agonist
that is widely used as a clinical anesthetic to induce anxiolytic, sedative, and analgesic …

Background and objective There is currently no FDA-approved medical therapy for delayed
graft function (DGF). Dexmedetomidine (DEX) has multiple reno-protective effects …

Introduction: Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy
(HIPEC) predispose to postoperative renal dysfunction. Dexmedetomidine is an α2 …

Background In this study we aimed to investigate the effects of dexmedetomidine on early
stage renal function in pediatric patients undergoing cardiac angiography. Methods 60 …

Objective To evaluate whether the use of intraoperative dexmedetomidine (DEX) during
lung cancer surgery may reduce the incidence of acute kidney injury (AKI). Design A …

Purpose To evaluate the effectivity and safety of percutaneous nephrolithotomy (PCNL) in
the treatment of solitary kidney with staghorn stones in prone position or in completely …