Artificial biocatalytic linear cascades for preparation of organic molecules

JH Schrittwieser, S Velikogne, M Hall… - Chemical …, 2018 - ACS Publications
The review compiles artificial cascades involving enzymes with a focus on the last 10 years.
A cascade is defined as the combination of at least two reaction steps in a single reaction …

Biocatalytic reduction reactions from a chemist's perspective

F Hollmann, DJ Opperman… - Angewandte Chemie …, 2021 - Wiley Online Library
Reductions play a key role in organic synthesis, producing chiral products with new
functionalities. Enzymes can catalyse such reactions with exquisite stereo‐, regio‐and …

Enzyme mimics: advances and applications

E Kuah, S Toh, J Yee, Q Ma… - Chemistry–A European …, 2016 - Wiley Online Library
Enzyme mimics or artificial enzymes are a class of catalysts that have been actively pursued
for decades and have heralded much interest as potentially viable alternatives to natural …

Construction of chemoenzymatic cascade reactions for bridging chemocatalysis and Biocatalysis: Principles, strategies and prospective

Y Liu, P Liu, S Gao, Z Wang, P Luan… - Chemical Engineering …, 2021 - Elsevier
Multi-step one-pot chemoenzymatic cascade reactions (mo-CECRs) bridging chemo-and
bio-catalysis can not only accomplish chemical transformations with minimized purification …

Chemoenzymatic cascades combining biocatalysis and transition metal catalysis for asymmetric synthesis

S González‐Granda, L Escot, I Lavandera… - Angewandte …, 2023 - Wiley Online Library
The combination of catalytic methods provides multiple advantages in organic synthesis,
allowing access to diverse organic molecules in a straightforward manner. Merging metal …

A supramolecular approach to combining enzymatic and transition metal catalysis

ZJ Wang, KN Clary, RG Bergman, KN Raymond… - Nature …, 2013 - nature.com
The ability of supramolecular host–guest complexes to catalyse organic reactions
collaboratively with an enzyme is an important goal in the research and discovery of …

Synthetic cascades are enabled by combining biocatalysts with artificial metalloenzymes

V Köhler, YM Wilson, M Dürrenberger, D Ghislieri… - Nature Chemistry, 2013 - nature.com
Enzymatic catalysis and homogeneous catalysis offer complementary means to address
synthetic challenges, both in chemistry and in biology. Despite its attractiveness, the …

Biocatalytic ketone reduction: a green and efficient access to enantiopure alcohols

Y Ni, JH Xu - Biotechnology advances, 2012 - Elsevier
Chiral secondary alcohols play an important role in pharmaceutical, agrochemical, and
chemical industries. In recent years, impressive steps forward have been achieved towards …

Enantioselective synthesis of amines by combining photoredox and enzymatic catalysis in a cyclic reaction network

X Guo, Y Okamoto, MR Schreier, TR Ward… - Chemical …, 2018 - pubs.rsc.org
Visible light-driven reduction of imines to enantioenriched amines in aqueous solution is
demonstrated for the first time. Excitation of a new water-soluble variant of the widely used [Ir …

Organometallic ruthenium and iridium transfer‐hydrogenation catalysts using coenzyme NADH as a cofactor

S Betanzos‐Lara, Z Liu, A Habtemariam… - Angewandte …, 2012 - Wiley Online Library
The rapidly develo** research area of bio-organometallic chemistry offers the possibility to
design compounds with a potentially wide range of applications in biology and medicine.[1] …