Autophagosome biogenesis: From membrane growth to closure

TJ Melia, AH Lystad, A Simonsen - Journal of Cell Biology, 2020 - rupress.org
Autophagosome biogenesis involves de novo formation of a membrane that elongates to
sequester cytoplasmic cargo and closes to form a double-membrane vesicle (an …

Hydrogen sulfide signaling in plants: emerging roles of protein persulfidation

A Aroca, C Gotor, LC Romero - Frontiers in Plant Science, 2018 - frontiersin.org
Hydrogen sulfide (H2S) has been largely referred as a toxic gas and environmental hazard,
but recent years, it has emerged as an important gas-signaling molecule with effects on …

Full-coverage regulations of autophagy by ROS: from induction to maturation

J Zhou, XY Li, YJ Liu, J Feng, Y Wu, HM Shen, GD Lu - Autophagy, 2022 - Taylor & Francis
Macroautophagy/autophagy is an evolutionarily well-conserved recycling process in
response to stress conditions, including a burst of reactive oxygen species (ROS) …

Autophagy: a key regulator of homeostasis and disease: an overview of molecular mechanisms and modulators

L Gómez-Virgilio, MC Silva-Lucero, DS Flores-Morelos… - Cells, 2022 - mdpi.com
Autophagy is a highly conserved lysosomal degradation pathway active at basal levels in all
cells. However, under stress conditions, such as a lack of nutrients or trophic factors, it works …

Recent insights into the mitochondrial role in autophagy and its regulation by oxidative stress

V Roca-Agujetas, C de Dios, L Lestón… - Oxidative medicine …, 2019 - Wiley Online Library
Autophagy is a self‐digestive process that degrades intracellular components, including
damaged organelles, to maintain energy homeostasis and to cope with cellular stress …

Hydrogen sulfide signaling in plant adaptations to adverse conditions: molecular mechanisms

A Aroca, J Zhang, Y **e, LC Romero… - Journal of Experimental …, 2021 - academic.oup.com
Hydrogen sulfide (H2S) is a signaling molecule that regulates critical processes and allows
plants to adapt to adverse conditions. The molecular mechanism underlying H2S action …

Autophagy-regulating protease Atg4: structure, function, regulation and inhibition

T Maruyama, NN Noda - The Journal of antibiotics, 2018 - nature.com
Autophagy is an intracellular degradation system that contributes to cellular homeostasis
through degradation of various targets such as proteins, organelles and microbes. Since …

Abscisic acid-triggered persulfidation of the Cys protease ATG4 mediates regulation of autophagy by sulfide

AM Laureano-Marín, Á Aroca, ME Pérez-Pérez… - The Plant …, 2020 - academic.oup.com
Hydrogen sulfide is a signaling molecule that regulates essential processes in plants, such
as autophagy. In Arabidopsis (Arabidopsis thaliana), hydrogen sulfide negatively regulates …

Persulfidation of ATG18a regulates autophagy under ER stress in Arabidopsis

A Aroca, I Yruela, C Gotor… - Proceedings of the …, 2021 - National Acad Sciences
Hydrogen sulfide (H2S) is an endogenously generated gaseous signaling molecule, which
recently has been implicated in autophagy regulation in both plants and mammals through …

Redox homeostasis, oxidative stress and mitophagy

C Garza-Lombó, A Pappa, MI Panayiotidis, R Franco - Mitochondrion, 2020 - Elsevier
Autophagy is a ubiquitous homeostatic mechanism for the degradation or turnover of cellular
components. Degradation of mitochondria via autophagy (mitophagy) is involved in a …