Recent advances in single-cell technologies have enabled high-throughput molecular
profiling of cells across modalities and locations. Single-cell transcriptomics data can now …

Doublets are prevalent in single-cell sequencing data and can lead to artifactual findings. A
number of strategies have therefore been proposed to detect them. Building on the strengths …

Human pluripotent stem (hPS) cells can, in theory, be differentiated into any cell type,
making them a powerful in vitro model for human biology. Recent technological advances …

Multiplexing across donors has emerged as a popular strategy to increase throughput,
reduce costs, overcome technical batch effects, and improve doublet detection in single-cell …

Successful pregnancy relies directly on the placenta's complex, dynamic, gene-regulatory
networks. Disruption of this vast collection of intercellular and intracellular programs leads to …

Sample multiplexing is often used to reduce cost and limit batch effects in single-cell RNA
sequencing (scRNA-seq) experiments. A commonly used multiplexing technique involves …

The mechanisms by which DNA alleles contribute to disease risk, drug response, and other
human phenotypes are highly context-specific, varying across cell types and different …

Single-cell RNA sequencing (scRNA-Seq) has emerged as a powerful tool for
understanding cellular heterogeneity and function. However the choice of sample …

The hypothalamus is a region of the brain that plays an important role in regulating body
functions and behaviors. There is a growing interest in human pluripotent stem cells …

Single-cell sequencing (sc-seq) provides a species agnostic tool to study cellular processes.
However, these technologies are expensive and require sufficient cell quantities and …