Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …

A brain–computer interface (BCI) establishes a direct communication channel between a
brain and an external device. With recent advances in neurotechnology and artificial …

Chronic pain syndromes are often refractory to treatment and cause substantial suffering
and disability. Pain severity is often measured through subjective report, while objective …

It is typically assumed that large networks of neurons exhibit a large repertoire of nonlinear
behaviours. Here we challenge this assumption by leveraging mathematical models derived …

Bioelectronics is a hot research topic, yet an important tool, as it facilitates the creation of
advanced medical devices that interact with biological systems to effectively diagnose …

Antidepressants are widely prescribed, but their efficacy relative to placebo is modest, in part
because the clinical diagnosis of major depression encompasses biologically …

Deep brain stimulation (DBS) is an effective treatment for common movement disorders and
has been used to modulate neural activity through delivery of electrical stimulation to key …

Brain–machine interfaces (BMIs) create closed-loop control systems that interact with the
brain by recording and modulating neural activity and aim to restore lost function, most …

Direct electrical stimulation can modulate the activity of brain networks for the treatment of
several neurological and neuropsychiatric disorders and for restoring lost function. However …

Neural activity exhibits complex dynamics related to various brain functions, internal states
and behaviors. Understanding how neural dynamics explain specific measured behaviors …