Psychedelic drugs: neurobiology and potential for treatment of psychiatric disorders

FX Vollenweider, KH Preller - Nature Reviews Neuroscience, 2020 - nature.com
Renewed interest in the use of psychedelics in the treatment of psychiatric disorders
warrants a better understanding of the neurobiological mechanisms underlying the effects of …

Treatment of posttraumatic stress disorder: A state-of-the-art review

L Burback, S Brult-Phillips, MJ Nijdam… - Current …, 2024 - benthamdirect.com
This narrative state-of-the-art review paper describes the progress in the understanding and
treatment of Posttraumatic Stress Disorder (PTSD). Over the last four decades, the scientific …

The therapeutic potential of psilocybin

H Lowe, N Toyang, B Steele, H Valentine, J Grant, A Ali… - Molecules, 2021 - mdpi.com
The psychedelic effects of some plants and fungi have been known and deliberately
exploited by humans for thousands of years. Fungi, particularly mushrooms, are the principal …

[HTML][HTML] REBUS and the anarchic brain: toward a unified model of the brain action of psychedelics

RL Carhart-Harris, KJ Friston - Pharmacological reviews, 2019 - Elsevier
This paper formulates the action of psychedelics by integrating the free-energy principle and
entropic brain hypothesis. We call this formulation relaxed beliefs under psychedelics …

Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies

KAA Andersen, R Carhart‐Harris… - Acta Psychiatrica …, 2021 - Wiley Online Library
Objective To conduct a systematic review of modern‐era (post‐millennium) clinical studies
assessing the therapeutic effects of serotonergic psychedelics drugs for mental health …

Efficacy and safety of psychedelics for the treatment of mental disorders: A systematic review and meta-analysis

Y Yao, D Guo, TS Lu, FL Liu, SH Huang, MQ Diao… - Psychiatry …, 2024 - Elsevier
We aim to systematically review and meta-analyze the effectiveness and safety of
psychedelics [psilocybin, ayahuasca (active component DMT), LSD and MDMA] in treating …

Reviewing the potential of psychedelics for the treatment of PTSD

E Krediet, T Bostoen, J Breeksema… - International Journal …, 2020 - academic.oup.com
There are few medications with demonstrated efficacy for the treatment of posttraumatic
stress disorder (PTSD). Treatment guidelines have unequivocally designated psychotherapy …

The entropic brain-revisited

RL Carhart-Harris - Neuropharmacology, 2018 - Elsevier
The entropic brain hypothesis proposes that within upper and lower limits, after which
consciousness may be lost, the entropy of spontaneous brain activity indexes the …

Hallucinogens in mental health: preclinical and clinical studies on LSD, psilocybin, MDMA, and ketamine

D De Gregorio, A Aguilar-Valles, KH Preller… - Journal of …, 2021 - jneurosci.org
A revamped interest in the study of hallucinogens has recently emerged, especially with
regard to their potential application in the treatment of psychiatric disorders. In the last …

Psychedelics

DE Nichols - Pharmacological reviews, 2016 - Elsevier
Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter
perception and mood and affect numerous cognitive processes. They are generally …