Astrocytes as key regulators of brain energy metabolism: new therapeutic perspectives

E Beard, S Lengacher, S Dias, PJ Magistretti… - Frontiers in …, 2022 - frontiersin.org
Astrocytes play key roles in the regulation of brain energy metabolism, which has a major
impact on brain functions, including memory, neuroprotection, resistance to oxidative stress …

Retinoblastoma origins and destinations

D Cobrinik - New England Journal of Medicine, 2024 - Mass Medical Soc
Retinoblastoma Origins and Destinations | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

Distribution of ACE2, CD147, CD26, and other SARS‐CoV‐2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension …

U Radzikowska, M Ding, G Tan, D Zhakparov, Y Peng… - Allergy, 2020 - Wiley Online Library
Background Morbidity and mortality from COVID‐19 caused by novel coronavirus SARS‐
CoV‐2 is accelerating worldwide, and novel clinical presentations of COVID‐19 are often …

Phenoty** and genoty** inherited retinal diseases: Molecular genetics, clinical and imaging features, and therapeutics of macular dystrophies, cone and cone-rod …

M Georgiou, AG Robson, K Fu**ami… - Progress in retinal and …, 2024 - Elsevier
Inherited retinal diseases (IRD) are a leading cause of blindness in the working age
population and in children. The scope of this review is to familiarise clinicians and scientists …

Early and late stage gene therapy interventions for inherited retinal degenerations

C Botto, M Rucli, MD Tekinsoy, J Pulman… - Progress in Retinal and …, 2022 - Elsevier
Inherited and age-related retinal degeneration is the hallmark of a large group of
heterogeneous diseases and is the main cause of untreatable blindness today. Genetic …

Retinitis pigmentosa: current clinical management and emerging therapies

XTA Nguyen, L Moekotte, AS Plomp… - International Journal of …, 2023 - mdpi.com
Retinitis pigmentosa (RP) comprises a group of inherited retinal dystrophies characterized
by the degeneration of rod photoreceptors, followed by the degeneration of cone …

Molecular genetics and emerging therapies for retinitis pigmentosa: Basic research and clinical perspectives

MF Dias, K Joo, JA Kemp, SL Fialho… - Progress in retinal and …, 2018 - Elsevier
Retinitis Pigmentosa (RP) is a hereditary retinopathy that affects about 2.5 million people
worldwide. It is characterized with progressive loss of rods and cones and causes severe …

Retina metabolism and metabolism in the pigmented epithelium: a busy intersection

JB Hurley - Annual review of vision science, 2021 - annualreviews.org
The outer retina is nourished from the choroid, a capillary bed just inside the sclera. O2,
glucose, and other nutrients diffuse out of the choroid and then filter through a monolayer of …

[HTML][HTML] Mechanisms of photoreceptor death in retinitis pigmentosa

F Newton, R Megaw - Genes, 2020 - mdpi.com
Retinitis pigmentosa (RP) is the most common cause of inherited blindness and is
characterised by the progressive loss of retinal photoreceptors. However, RP is a highly …

[HTML][HTML] Mitophagy in the retina: viewing mitochondrial homeostasis through a new lens

JI Jiménez-Loygorri, R Benítez-Fernández… - Progress in retinal and …, 2023 - Elsevier
Mitochondrial function is key to support metabolism and homeostasis in the retina, an organ
that has one of the highest metabolic rates body-wide and is constantly exposed to …