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Astrocytes as key regulators of brain energy metabolism: new therapeutic perspectives
Astrocytes play key roles in the regulation of brain energy metabolism, which has a major
impact on brain functions, including memory, neuroprotection, resistance to oxidative stress …
impact on brain functions, including memory, neuroprotection, resistance to oxidative stress …
Retinoblastoma origins and destinations
D Cobrinik - New England Journal of Medicine, 2024 - Mass Medical Soc
Retinoblastoma Origins and Destinations | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …
content The New England Journal of Medicine homepage Advanced Search SEARCH …
Distribution of ACE2, CD147, CD26, and other SARS‐CoV‐2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension …
Background Morbidity and mortality from COVID‐19 caused by novel coronavirus SARS‐
CoV‐2 is accelerating worldwide, and novel clinical presentations of COVID‐19 are often …
CoV‐2 is accelerating worldwide, and novel clinical presentations of COVID‐19 are often …
Phenoty** and genoty** inherited retinal diseases: Molecular genetics, clinical and imaging features, and therapeutics of macular dystrophies, cone and cone-rod …
Inherited retinal diseases (IRD) are a leading cause of blindness in the working age
population and in children. The scope of this review is to familiarise clinicians and scientists …
population and in children. The scope of this review is to familiarise clinicians and scientists …
Early and late stage gene therapy interventions for inherited retinal degenerations
C Botto, M Rucli, MD Tekinsoy, J Pulman… - Progress in Retinal and …, 2022 - Elsevier
Inherited and age-related retinal degeneration is the hallmark of a large group of
heterogeneous diseases and is the main cause of untreatable blindness today. Genetic …
heterogeneous diseases and is the main cause of untreatable blindness today. Genetic …
Retinitis pigmentosa: current clinical management and emerging therapies
XTA Nguyen, L Moekotte, AS Plomp… - International Journal of …, 2023 - mdpi.com
Retinitis pigmentosa (RP) comprises a group of inherited retinal dystrophies characterized
by the degeneration of rod photoreceptors, followed by the degeneration of cone …
by the degeneration of rod photoreceptors, followed by the degeneration of cone …
Molecular genetics and emerging therapies for retinitis pigmentosa: Basic research and clinical perspectives
MF Dias, K Joo, JA Kemp, SL Fialho… - Progress in retinal and …, 2018 - Elsevier
Retinitis Pigmentosa (RP) is a hereditary retinopathy that affects about 2.5 million people
worldwide. It is characterized with progressive loss of rods and cones and causes severe …
worldwide. It is characterized with progressive loss of rods and cones and causes severe …
Retina metabolism and metabolism in the pigmented epithelium: a busy intersection
JB Hurley - Annual review of vision science, 2021 - annualreviews.org
The outer retina is nourished from the choroid, a capillary bed just inside the sclera. O2,
glucose, and other nutrients diffuse out of the choroid and then filter through a monolayer of …
glucose, and other nutrients diffuse out of the choroid and then filter through a monolayer of …
[HTML][HTML] Mechanisms of photoreceptor death in retinitis pigmentosa
F Newton, R Megaw - Genes, 2020 - mdpi.com
Retinitis pigmentosa (RP) is the most common cause of inherited blindness and is
characterised by the progressive loss of retinal photoreceptors. However, RP is a highly …
characterised by the progressive loss of retinal photoreceptors. However, RP is a highly …
[HTML][HTML] Mitophagy in the retina: viewing mitochondrial homeostasis through a new lens
JI Jiménez-Loygorri, R Benítez-Fernández… - Progress in retinal and …, 2023 - Elsevier
Mitochondrial function is key to support metabolism and homeostasis in the retina, an organ
that has one of the highest metabolic rates body-wide and is constantly exposed to …
that has one of the highest metabolic rates body-wide and is constantly exposed to …