Recent progress, methods and perspectives in forensic epigenetics

A Vidaki, M Kayser - Forensic Science International: Genetics, 2018 - Elsevier
Forensic epigenetics, ie, investigating epigenetics variation to resolve forensically relevant
questions unanswerable with standard forensic DNA profiling has been gaining substantial …

From forensic epigenetics to forensic epigenomics: broadening DNA investigative intelligence

A Vidaki, M Kayser - Genome biology, 2017 - Springer
Human genetic variation is a major resource in forensics, but does not allow all forensically
relevant questions to be answered. Some questions may instead be addressable via …

Epigenetic age prediction in semen–marker selection and model development

A Pisarek, E Pośpiech, A Heidegger… - Aging (Albany …, 2021 - pmc.ncbi.nlm.nih.gov
DNA methylation analysis is becoming increasingly useful in biomedical research and
forensic practice. The discovery of differentially methylated sites (DMSs) that continuously …

Proof of concept study of age-dependent DNA methylation markers across different tissues by massive parallel sequencing

J Naue, T Sänger, HCJ Hoefsloot… - Forensic Science …, 2018 - Elsevier
The use of DNA methylation (DNAm) for chronological age determination has been widely
investigated within the last few years for its application within the field of forensic genetics …

Uncovering forensic evidence: a path to age estimation through DNA methylation

MJ Castagnola, F Medina-Paz, SC Zapico - International Journal of …, 2024 - mdpi.com
Age estimation is a critical aspect of reconstructing a biological profile in forensic sciences.
Diverse biochemical processes have been studied in their correlation with age, and the …

A review about transcription factor binding sites prediction based on deep learning

Y Zeng, M Gong, M Lin, D Gao, Y Zhang - Ieee Access, 2020 - ieeexplore.ieee.org
Transcription factors (TFs) recognize and bind to specific DNA sequences, thereby altering
the chromatin structure and regulating transcription. TFs aid in the formation of a guide …

A review of bioinformatic methods for forensic DNA analyses

YY Liu, SA Harbison - Forensic Science International: Genetics, 2018 - Elsevier
Short tandem repeats, single nucleotide polymorphisms, and whole mitochondrial analyses
are three classes of markers which will play an important role in the future of forensic DNA …

Lighting up forensic science by aggregation-induced emission: A review

Y Yan, J Zhang, S Yi, L Liu, C Huang - Analytica Chimica Acta, 2021 - Elsevier
Forensic science requires a fast, sensitive, and anti-interfering imaging tool for on-site
investigation and bio-analysis. The aggregation-induced emission (AIE) phenomenon …

[HTML][HTML] Targeted DNA methylation analysis and prediction of smoking habits in blood based on massively parallel sequencing

A Vidaki, BP Jiménez, B Poggiali, V Kalamara… - Forensic Science …, 2023 - Elsevier
Tobacco smoking is a frequent habit sustained by> 1.3 billion people in 2020 and the
leading preventable factor for health risk and premature mortality worldwide. In the forensic …

Discrimination of monozygotic twins using mtDNA heteroplasmy through probe capture enrichment and massively parallel sequencing

Y Zhong, K Zeng, A Adnan, YZ Li, X Hou, Y Pan… - International Journal of …, 2023 - Springer
Differentiating between monozygotic (MZ) twins remains difficult because they have the
same genetic makeup. Applying the traditional STR genoty** approach cannot …