The matrilins: modulators of extracellular matrix assembly

AR Klatt, AKA Becker, CD Neacsu, M Paulsson… - The international journal …, 2011 - Elsevier
The matrilins form a family of oligomeric extracellular adaptor proteins that are most strongly
expressed in cartilage but also present in many other extracellular matrices. Matrilins bind to …

[HTML][HTML] The matrilins–adaptor proteins in the extracellular matrix

R Wagener, HWA Ehlen, YP Ko, B Kobbe, HH Mann… - FEBS letters, 2005 - Elsevier
The matrilins form a four-member family of modular, multisubunit matrix proteins, which are
expressed in cartilage but also in many other forms of extracellular matrix. They participate …

Myeloid-related proteins 8 and 14 induce a specific inflammatory response in human microvascular endothelial cells

D Viemann, A Strey, A Janning, K Jurk, K Klimmek… - Blood, 2005 - ashpublications.org
Abstract Myeloid-related protein 8 (MRP8) and MRP14, S100 proteins secreted by activated
phagocytes, bind specifically to endothelial cells. The endothelial response to …

Complexes of matrilin-1 and biglycan or decorin connect collagen VI microfibrils to both collagen II and aggrecan

C Wiberg, AR Klatt, R Wagener, M Paulsson… - Journal of Biological …, 2003 - ASBMB
Native supramolecular assemblies containing collagen VI microfibrils and associated
extracellular matrix proteins were isolated from Swarm rat chondrosarcoma tissue. Their …

Steroid and Xenobiotic Receptor SXR Mediates Vitamin K2-activated Transcription of Extracellular Matrix-related Genes and Collagen Accumulation in Osteoblastic …

T Ichikawa, K Horie-Inoue, K Ikeda, B Blumberg… - Journal of Biological …, 2006 - ASBMB
Vitamin K 2 is a critical nutrient required for blood coagulation. It also plays a key role in
bone homeostasis and is a clinically effective therapeutic agent for osteoporosis. We …

Altered integration of matrilin-3 into cartilage extracellular matrix in the absence of collagen IX

B Budde, K Blumbach, J Ylöstalo, F Zaucke… - … and cellular biology, 2005 - Taylor & Francis
The matrilins are a family of four noncollagenous oligomeric extracellular matrix proteins
with a modular structure. Matrilins can act as adapters which bridge different …

Molecular structure and tissue distribution of matrilin-3, a filament-forming extracellular matrix protein expressed during skeletal development

AR Klatt, DP Nitsche, B Kobbe, M Mörgelin… - Journal of Biological …, 2000 - ASBMB
Matrilin-3 is a recently identified member of the superfamily of proteins containing von
Willebrand factor A-like domains and is able to form hetero-oligomers with matrilin-1 …

Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis

L van der Weyden, L Wei, J Luo, X Yang… - The American journal of …, 2006 - Elsevier
Mutations in the gene encoding matrilin-3 (MATN3), a noncollagenous extracellular matrix
protein, have been reported in a variety of skeletal diseases, including multiple epiphyseal …

Mice lacking the matrilin family of extracellular matrix proteins develop mild skeletal abnormalities and are susceptible to age-associated osteoarthritis

P Li, L Fleischhauer, C Nicolae, C Prein… - International journal of …, 2020 - mdpi.com
Matrilins (MATN1, MATN2, MATN3 and MATN4) are adaptor proteins of the cartilage
extracellular matrix (ECM), which bridge the collagen II and proteoglycan networks. In …

An invasion-independent pathway of blood-borne metastasis: a new murine mammary tumor model

T Sugino, T Kusakabe, N Hoshi, T Yamaguchi… - The American journal of …, 2002 - Elsevier
It is generally believed that active invasion by cancer cells is essential to the metastatic
process. In this report, we describe a murine mammary tumor (MCH66) model of metastasis …