Functional evaluation of peripheral nerve regeneration and target reinnervation in animal models: a critical overview

X Navarro - European Journal of Neuroscience, 2016 - Wiley Online Library
Peripheral nerve injuries usually lead to severe loss of motor, sensory and autonomic
functions in the patients. Due to the complex requirements for adequate axonal …

Rodent, large animal and non-human primate models of spinal cord injury

R Nardone, C Florea, Y Höller, F Brigo, V Versace… - Zoology, 2017 - Elsevier
In this narrative review we aimed to assess the usefulness of the different animal models in
identifying injury mechanisms and develo** therapies for humans suffering from spinal …

A mouse model of non-motor symptoms in Parkinson's disease: focus on pharmacological interventions targeting affective dysfunctions

A Bonito-Oliva, D Masini, G Fisone - Frontiers in behavioral …, 2014 - frontiersin.org
Non-motor symptoms, including psychiatric disorders, are increasingly recognized as a
major challenge in the treatment of Parkinson's disease (PD). These ailments, which often …

Necroptosis inhibitor necrostatin-1 promotes cell protection and physiological function in traumatic spinal cord injury

Y Wang, H Wang, Y Tao, S Zhang, J Wang, X Feng - Neuroscience, 2014 - Elsevier
Spinal cord injury (SCI) is a common and serious trauma which lacks efficient treatment.
Inhibition of cell death in the trauma area is important for spinal cord protection during this …

Rehabilitative training in animal models of spinal cord injury

A Torres-Espín, E Beaudry, K Fenrich… - Journal of …, 2018 - liebertpub.com
Rehabilitative motor training is currently one of the most widely used approaches to promote
moderate recovery following injuries of the central nervous system. Such training is …

Bone marrow mesenchymal stromal cells and olfactory ensheathing cells transplantation after spinal cord injury–a morphological and functional comparison in rats

A Torres‐Espín, E Redondo‐Castro… - European Journal of …, 2014 - Wiley Online Library
Cell therapy for spinal cord injury (SCI) is a promising strategy for clinical application. Both
bone marrow mesenchymal stromal cells (MSC s; also known as bone marrow‐derived …

Spinal control of locomotion before and after spinal cord injury

SM Danner, CT Shepard, C Hainline… - Experimental …, 2023 - Elsevier
Thoracic spinal cord injury affects long propriospinal neurons that interconnect the cervical
and lumbar enlargements. These neurons are crucial for coordinating forelimb and hindlimb …

Immunosuppression of allogenic mesenchymal stem cells transplantation after spinal cord injury improves graft survival and beneficial outcomes

A Torres-Espin, E Redondo-Castro… - Journal of …, 2015 - liebertpub.com
Cell therapy for spinal cord injury (SCI) is a promising strategy for clinical application.
Mesenchymal stem cells (MSC) have demonstrated beneficial effects following …

A novel closed-body model of spinal cord injury caused by high-pressure air blasts produces extensive axonal injury and motor impairments

N del Mar, X von Buttlar, SY Angela, NH Guley… - Experimental …, 2015 - Elsevier
Diffuse axonal injury is thought to be the basis of the functional impairments stemming from
mild traumatic brain injury. To examine how axons are damaged by traumatic events, such …

Chronic ibuprofen administration reduces neuropathic pain but does not exert neuroprotection after spinal cord injury in adult rats

E Redondo-Castro, X Navarro - Experimental neurology, 2014 - Elsevier
Ibuprofen is commonly used as an anti-inflammatory analgesic drug, although it is not
amongst the first-line treatments for neuropathic pain. Its main effects are mediated by non …