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Data‐and theory‐driven approaches for understanding paths of epithelial–mesenchymal transition
Reversible transitions between epithelial and mesenchymal cell states are a crucial form of
epithelial plasticity for development and disease progression. Recent experimental data and …
epithelial plasticity for development and disease progression. Recent experimental data and …
SpottedPy quantifies relationships between spatial transcriptomic hotspots and uncovers environmental cues of epithelial-mesenchymal plasticity in breast cancer
Spatial transcriptomics is revolutionizing the exploration of intratissue heterogeneity in
cancer, yet capturing cellular niches and their spatial relationships remains challenging. We …
cancer, yet capturing cellular niches and their spatial relationships remains challenging. We …
Soluble guanylate cyclase dysfunction and nitric oxide pathway in chronic rhinosinusitis with nasal polyps: predictive markers for postoperative recurrence
S Jiang, MD, C Zhang, MD… - American Journal of …, 2025 - journals.sagepub.com
Background Elevated nitric oxide (NO) levels have been linked to a heightened risk of
recurrence in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). However, the …
recurrence in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). However, the …
WENDY: Covariance dynamics based gene regulatory network inference
Determining gene regulatory network (GRN) structure is a central problem in biology, with a
variety of inference methods available for different types of data. For a widely prevalent and …
variety of inference methods available for different types of data. For a widely prevalent and …
SpottedPy quantifies relationships between spatial transcriptomic hotspots and uncovers new environmental cues of epithelial-mesenchymal plasticity in cancer
Spatial transcriptomics is revolutionising our ability to explore intratissue heterogeneity in
cancer, but methods that can effectively capture cancer cell niches and explore their …
cancer, but methods that can effectively capture cancer cell niches and explore their …
TRENDY: Gene Regulatory Network Inference Enhanced by Transformer
Gene regulatory networks (GRNs) play a crucial role in the control of cellular functions.
Numerous methods have been developed to infer GRNs from gene expression data …
Numerous methods have been developed to infer GRNs from gene expression data …
WENDY: Gene Regulatory Network Inference with Covariance Dynamics
Determining the structure of gene regulatory networks (GRNs) is a central problem in
biology, with a variety of inference methods available for different types of data. However, for …
biology, with a variety of inference methods available for different types of data. However, for …