Natural compounds as potential adjuvants to cancer therapy: Preclinical evidence

SR Lin, CH Chang, CF Hsu, MJ Tsai… - British journal of …, 2020 - Wiley Online Library
Traditional chemotherapy is being considered due to hindrances caused by systemic
toxicity. Currently, the administration of multiple chemotherapeutic drugs with different …

Adverse effects of tyrosine kinase inhibitors in cancer therapy: pathophysiology, mechanisms and clinical management

S Shyam Sunder, UC Sharma… - Signal Transduction and …, 2023 - nature.com
Since their invention in the early 2000s, tyrosine kinase inhibitors (TKIs) have gained
prominence as the most effective pathway-directed anti-cancer agents. TKIs have shown …

Role of serum biomarkers in cancer patients receiving cardiotoxic cancer therapies: a position statement from the Cardio‐Oncology Study Group of the Heart Failure …

R Pudil, C Mueller, J Čelutkienė… - European journal of …, 2020 - Wiley Online Library
Serum biomarkers are an important tool in the baseline risk assessment and diagnosis of
cardiovascular disease in cancer patients receiving cardiotoxic cancer treatments. Increases …

Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin

K Hou, J Shen, J Yan, C Zhai, J Zhang, JA Pan… - …, 2021 - thelancet.com
Background Doxorubicin, an anthracycline chemotherapeutic agent, is widely used in the
treatment of many cancers. However, doxorubicin posts a great risk of adverse …

Functionalized chitosan for cancer nano drug delivery

Y Zaiki, A Iskandar, TW Wong - Biotechnology Advances, 2023 - Elsevier
Chitosan is a biotechnological derivative of chitin receiving a widespread pharmaceutical
and biomedical applications. It can be used to encapsulate and deliver cancer therapeutics …

The double-edged sword of oxidative stress in skin damage and melanoma: From physiopathology to therapeutical approaches

M Emanuelli, D Sartini, E Molinelli, R Campagna… - Antioxidants, 2022 - mdpi.com
The skin is constantly exposed to exogenous and endogenous sources of reactive oxygen
species (ROS). An adequate balance between ROS levels and antioxidant defenses is …

Nanocarriers for the delivery of medical, veterinary, and agricultural active ingredients

PL Chariou, OA Ortega-Rivera, NF Steinmetz - Acs Nano, 2020 - ACS Publications
Nanocarrier-based delivery systems can be used to increase the safety and efficacy of active
ingredients in medical, veterinary, or agricultural applications, particularly when such …

Metabolic aspects of anthracycline cardiotoxicity

M Russo, A Della Sala, CG Tocchetti… - … treatment options in …, 2021 - Springer
Opinion statement Heart failure (HF) is increasingly recognized as the major complication of
chemotherapy regimens. Despite the development of modern targeted therapies such as …

Future needs in mast cell biology

G Varricchi, A de Paulis, G Marone, SJ Galli - International journal of …, 2019 - mdpi.com
The pathophysiological roles of mast cells are still not fully understood, over 140 years since
their description by Paul Ehrlich in 1878. Initial studies have attempted to identify distinct …

Gender differences in oxidative stress in relation to cancer susceptibility and survival

A Allegra, S Caserta, S Genovese, G Pioggia… - Antioxidants, 2023 - mdpi.com
Genetic, developmental, biochemical, and environmental variables interact intricately to
produce sex differences. The significance of sex differences in cancer susceptibility is being …