Deep eutectic solvents (DESs) are an emerging class of mixtures characterized by
significant depressions in melting points compared to those of the neat constituent …

Alarming statistics showing the continuous increase in the number of drugs and drug
candidates with insufficient water-solubility focus scientist's efforts on finding optimal strategy …

Glycerol–water mixtures were studied at molar concentrations ranging from xgly= 1 (neat
glycerol) to xgly= 0.3 using shear mechanical spectroscopy. We observed a low frequency …

Dielectric spectroscopy, rheology, and differential scanning calorimetry were employed to
study the effect of chain-end hydrogen bonding on the dynamics of hydroxyl-terminated …

Rational selection of polymers for amorphous drug stabilization is necessary for further
successful development of solid dispersion technology. In this paper, we investigate the …

The present work focusses on the molecular mobility characterization of amorphous N-acetyl-
α-methylbenzylamine (Nac-MBA) by Broadband Dielectric Relaxation Spectroscopy (DRS) …

In the case of formulations with amorphous active pharmaceutical ingredients the risk of
pressure-induced recrystallization should be carefully considered. We reported here that …

In this paper, we thoroughly investigated the physical stability of the anti-inflammatory drug
etoricoxib, which has been reported earlier to be resistant to recrystallization in its glassy …

Alkylacetamide-based model peptides display an intense Debye-type dielectric relaxation.
In order to explore the extent to which this feature has to be regarded analogous to that in …

Broadband dielectric spectroscopy (BDS), combined with the X-ray diffraction (XRD) and
Fourier transform infrared (FTIR) techniques, was used to study the dynamics of the primary …