Targeted immunotherapy has improved patient survival in head and neck squamous cell
carcinoma (HNSCC), but less than 20% of patients produce a durable response to these …

Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …

Cancer development is an evolutionary process. A key selection pressure is exerted by
therapy, one of the few players in cancer evolution that can be controlled. As such, an …

Objective To investigate the role of ferroptosis, an iron-dependent form of non-apoptotic cell
death, in the head and neck squamous cell carcinoma (HNSCC) immune microenvironment …

Cholangiocarcinoma (CCA), a highly lethal and fetal cancer derived from the hepatobiliary
system, is featured by aggressive growth and early lymphatic metastasis. Elucidating the …

Background Head and neck cancers (HNSCC) are highly immunosuppressive. Plasma-
derived exosomes of HNSCC patients carry immunomodulatory molecules, and their cargo …

There is increasing evidence that the spatial organization of cells within the tumor-immune
microenvironment (TiME) of solid tumors influences survival and response to therapy in …

Immune microenvironment could affect the biological progress in prostate cancer (PCa)
through N6 methyl adenosine (m6A) methylation. The purpose of this study was to …

Simple Summary Tumors are ecosystems composed of cancer cells and non-tumor stroma
together in a hypoxic environment often described as wounds that do not heal. Accumulating …

Head and neck squamous cell carcinoma (HNSCC) is one of the most common tumor
entities worldwide, with human papillomavirus (HPV) infection contributing to cancer …