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Gut microbiota role in irritable bowel syndrome: New therapeutic strategies
In the last decade the impressive expansion of our knowledge of the vast microbial
community that resides in the human intestine, the gut microbiota, has provided support to …
community that resides in the human intestine, the gut microbiota, has provided support to …
A role for the gut microbiota in IBS
The past decade has witnessed an explosion of knowledge regarding the vast microbial
community that resides within our intestine—the gut microbiota. The topic has generated …
community that resides within our intestine—the gut microbiota. The topic has generated …
Bowel disorders
Functional bowel disorders are highly prevalent disorders found worldwide. These disorders
have the potential to affect all members of society, regardless of age, sex, race, creed, color …
have the potential to affect all members of society, regardless of age, sex, race, creed, color …
Cytokine imbalance in irritable bowel syndrome: a systematic review and meta‐analysis
Background Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder of
unknown etiology; although infection and inflammation have recently been considered as …
unknown etiology; although infection and inflammation have recently been considered as …
Irritable bowel syndrome in children: Current knowledge, challenges and opportunities
Irritable bowel syndrome (IBS) is a common and troublesome disorder in children with an
increasing prevalence noted during the past two decades. It has a significant effect on the …
increasing prevalence noted during the past two decades. It has a significant effect on the …
Crosstalk at the mucosal border: importance of the gut microenvironment in IBS
The aetiology and pathology of IBS, a functional bowel disorder thought to lack an organic
cause, is largely unknown. However, studies suggest that various features, such as altered …
cause, is largely unknown. However, studies suggest that various features, such as altered …
Immune activation in irritable bowel syndrome: can neuroimmune interactions explain symptoms?
Irritable bowel syndrome (IBS) is a functional disorder of the gastrointestinal (GI) tract
characterized by pain or discomfort from the lower abdominal region, which is associated …
characterized by pain or discomfort from the lower abdominal region, which is associated …
Lessons learned—resolving the enigma of genetic factors in IBS
IBS is the most prevalent functional gastrointestinal disorder and phenotypically
characterized by chronic abdominal discomfort, pain and altered defecation patterns. The …
characterized by chronic abdominal discomfort, pain and altered defecation patterns. The …
Interleukin-6 in irritable bowel syndrome: A systematic review and meta-analysis of IL-6 (-G174C) and circulating IL-6 levels
Background Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder
which presents with abdominal pain and alterations of the bowel habits. The …
which presents with abdominal pain and alterations of the bowel habits. The …
Mast cells are increased in the small intestinal mucosa of patients with irritable bowel syndrome: a systematic review and meta‐analysis
Background Colonic mast cells have been proposed to be related to the pathophysiology of
irritable bowel syndrome (IBS). Whether mast cell counts are altered in the small intestine, a …
irritable bowel syndrome (IBS). Whether mast cell counts are altered in the small intestine, a …