Most cells respond to viral infections by activating innate immune pathways that lead to the
induction of antiviral restriction factors. One such factor, viperin, was discovered almost two …

Bacterial Kidney Disease (BKD), which is caused by a Gram-positive, intracellular bacterial
pathogen (Renibacterium salmoninarum), affects salmonids including Atlantic salmon …

Renibacterium salmoninarum is a Gram-positive, intracellular bacterial pathogen that
causes Bacterial Kidney Disease (BKD) in Atlantic salmon (Salmo salar). The host …

Viperin is an important virus-induced protein in animals that negatively participates in RNA
viral replication and transcription. The reactive machinery of viperin suggests that it …

A relatively large repertoire of type I interferon (IFN) genes is apparent in rainbow
trout/Atlantic salmon, that includes six different IFN subgroups (IFNa-IFNf) belonging to the …

Viperin, also known as radical S-Adenosyl methionine domain containing 2 (RSAD2), is an
IFN stimulated protein that plays crucial roles in innate immunity. Here, we identified a …

Background Antibody affinity maturation in vertebrates requires the enzyme activation-
induced cytidine deaminase (AID) which initiates secondary antibody diversification by …

Lepeophtheirus salmonis (sea lice) and bacterial co-infection threatens wild and farmed
Atlantic salmon performance and welfare. In the present study, pre-adult L. salmonis …

The radical S-adenosyl methionine domain-containing protein 2 (RSAD2), also known as
viperin, plays a momentous and multifaceted role in antiviral immunity. However, the …

Polyploidy and subsequent diploidization provide genomic opportunities for evolutionary
innovations and adaptation. The researches on duplicated gene evolutionary fates in …