The replication of the chromosome is among the most essential functions of the bacterial cell
and influences many other cellular mechanisms, from gene expression to cell division. Yet …

Since the first archaeal genome was sequenced, much attention has been focused on the
study of these unique microorganisms. We have learnt that although archaeal DNA …

Eukaryotic chromosomes possess multiple origins of replication, whereas bacterial
chromosomes are replicated from a single origin. The archaeon Pyrococcus abyssi also …

Polyploidy is common in higher eukaryotes, especially in plants, but it is generally assumed
that most prokaryotes contain a single copy of a circular chromosome and are therefore …

▪ Abstract Genome sequences of a number of archaea have revealed an apparent paradox
in the phylogenies of the bacteria, archaea, and eukarya, as well as an intriguing set of …

Growth and proliferation of all cell types require intricate regulation and coordination of
chromosome replication, genome segregation, cell division and the systems that determine …

To predict origins of replication in prokaryotic chromosomes, we analyse the leading and
lagging strands of 200 chromosomes for differences in oligomer composition and show that …

As the replication of genomic DNA is arguably the most important task performed by a cell
and given that it is controlled at the initiation stage, the events that occur at the replication …

The Z-curve is a three-dimensional curve that constitutes a unique representation of a DNA
sequence, ie, both the Z-curve and the given DNA sequence can be uniquely reconstructed …

Cell division is mediated by different mechanisms in different evolutionary lineages. While
bacteria and euryarchaea utilize an FtsZ‐based mechanism, most crenarchaea divide using …