Phenylketonuria (PKU) is an autosomal recessive inborn error of phenylalanine metabolism
caused by deficiency in the enzyme phenylalanine hydroxylase that converts phenylalanine …

With continued efforts to find solutions to rising rates of obesity and diabetes, there is
increased interest in the potential health benefits of the use of low-and no-calorie …

Background: The consumption of sucrose-sweetened soft drinks (SSSDs) has been
associated with obesity, the metabolic syndrome, and cardiovascular disorders in …

We developed European guidelines to optimise phenylketonuria (PKU) care. To develop the
guidelines, we did a literature search, critical appraisal, and evidence grading according to …

Background: Sugar-sweetened beverages are risk factors for type 2 diabetes; however, the
role of artificially sweetened beverages is unclear. Objective: The objective was to examine …

We report the effects of aspartame on anxiety-like behavior, neurotransmitter signaling and
gene expression in the amygdala, a brain region associated with the regulation of anxiety …

Aspartame is a sweetener introduced to replace the commonly used sucrose. It was
discovered by James M. Schlatter in 1965. Being 180–200 times sweeter than sucrose, its …

Molecularly imprinted materials are man-made mimics of biological receptors. Their polymer
network has recognition sites complementary to a substrate in terms of size, shape and …

The topic of gut microbiota and the microbiota-gut-brain (MGB) axis has become the
forefront of research and reports in the past few years. The gut microbiota is a dynamic …

Human populations are chronically exposed to mixtures of toxic chemicals. Predicting the
health effects of these mixtures require a large amount of information on the mode of action …