Women are about twice as likely as are men to develop depression during their lifetime. This
Series paper summarises evidence regarding the epidemiology on gender differences in …

Abstract The Research Domain Criteria (RDoC) and the Hierarchical Taxonomy of
Psychopathology (HiTOP) represent major dimensional frameworks proposing two …

A functional interplay of bottom‐up and top‐down processing allows an individual to
appropriately respond to the dynamic environment around them. These processing …

Behavioral testing constitutes the primary method to measure the emotional states of
nonhuman animals in preclinical research. Emerging as the characteristic tool of the …

Background Research suggests that the positive affect system may be an important yet
underexplored treatment target in anxiety and depression. Existing interventions primarily …

Obesity and mood disorders are highly prevalent and co-morbid. Epidemiological studies
have highlighted the public health relevance of this association, insofar as both conditions …

Posttraumatic stress disorder (PTSD) is a significant public health issue. Yet, there are
limited treatment options and no data to suggest which treatment will work for whom. We …

Abstract The United States National Institute of Mental Health has recently promoted the
Research Domain Criteria framework, which emphasizes the study of neurocognitive …

Depression is well known to share a negative cross-sectional relationship with personality
constructs defined by positive emotion (positive affect, extraversion, behavioral activation) …

Early adverse experiences are associated with heighted vulnerability for stress-related
psychopathology across the lifespan. While extensive work has investigated the effects of …