Microfluidics in vascular biology research: a critical review for engineers, biologists, and clinicians
G Simitian, M Virumbrales-Muñoz… - Lab on a Chip, 2022 - pubs.rsc.org
Neovascularization, the formation of new blood vessels, has received much research
attention due to its implications for physiological processes and diseases. Most studies …
attention due to its implications for physiological processes and diseases. Most studies …
The biophysics and mechanics of blood from a materials perspective
Cells actively interact with their microenvironment, constantly sensing and modulating
biochemical and biophysical signals. Blood comprises a variety of non-adherent cells that …
biochemical and biophysical signals. Blood comprises a variety of non-adherent cells that …
Hypothermal opto-thermophoretic tweezers
Optical tweezers have profound importance across fields ranging from manufacturing to
biotechnology. However, the requirement of refractive index contrast and high laser power …
biotechnology. However, the requirement of refractive index contrast and high laser power …
iCLOTS: open-source, artificial intelligence-enabled software for analyses of blood cells in microfluidic and microscopy-based assays
While microscopy-based cellular assays, including microfluidics, have significantly
advanced over the last several decades, there has not been concurrent development of …
advanced over the last several decades, there has not been concurrent development of …
Vascularized microfluidics and their untapped potential for discovery in diseases of the microvasculature
Microengineering advances have enabled the development of perfusable, endothelialized
models of the microvasculature that recapitulate the unique biological and biophysical …
models of the microvasculature that recapitulate the unique biological and biophysical …
Microfluidic electrical impedance assessment of red blood cell-mediated microvascular occlusion
Alterations in the deformability of red blood cells (RBCs), occurring in hemolytic blood
disorders such as sickle cell disease (SCD), contribute to vaso-occlusion and disease …
disorders such as sickle cell disease (SCD), contribute to vaso-occlusion and disease …
Lactated Ringer vs normal saline solution during sickle cell vaso-occlusive episodes
Importance Sickle cell disease (SCD), a clinically heterogenous genetic hemoglobinopathy,
is characterized by painful vaso-occlusive episodes (VOEs) that can require hospitalization …
is characterized by painful vaso-occlusive episodes (VOEs) that can require hospitalization …
Vascularized microfluidics and the blood–endothelium interface
The microvasculature is the primary conduit through which the human body transmits
oxygen, nutrients, and other biological information to its peripheral tissues. It does this …
oxygen, nutrients, and other biological information to its peripheral tissues. It does this …
[HTML][HTML] Perioperative management of sickle cell disease
KO Adjepong, F Otegbeye… - Mediterranean journal of …, 2018 - ncbi.nlm.nih.gov
Over 30 million people worldwide have sickle cell disease (SCD). Emergent and non-
emergent surgical procedures in SCD have been associated with relatively increased risks …
emergent surgical procedures in SCD have been associated with relatively increased risks …
Fluid overload due to intravenous fluid therapy for vaso‐occlusive crisis in sickle cell disease: incidence and risk factors
AE Gaartman, AK Sayedi, JJ Gerritsma… - British journal of …, 2021 - Wiley Online Library
Intravenous fluid therapy (IV‐FT) is routinely used in the treatment of vaso‐occlusive crises
(VOCs), as dehydration possibly promotes and sustains erythrocyte sickling. Patients with …
(VOCs), as dehydration possibly promotes and sustains erythrocyte sickling. Patients with …