Age-related macular degeneration
Age-related macular degeneration is a leading cause of visual impairment and severe vision
loss. Clinically, it is classified as early-stage (medium-sized drusen and retinal pigmentary …
loss. Clinically, it is classified as early-stage (medium-sized drusen and retinal pigmentary …
[HTML][HTML] Retinal stem cell transplantation: Balancing safety and potential
Stem cell transplantation holds great promise as a potential treatment for currently incurable
retinal degenerative diseases that cause poor vision and blindness. Recently, safety data …
retinal degenerative diseases that cause poor vision and blindness. Recently, safety data …
DeepSeeNet: a deep learning model for automated classification of patient-based age-related macular degeneration severity from color fundus photographs
Purpose In assessing the severity of age-related macular degeneration (AMD), the Age-
Related Eye Disease Study (AREDS) Simplified Severity Scale predicts the risk of …
Related Eye Disease Study (AREDS) Simplified Severity Scale predicts the risk of …
[HTML][HTML] Dynamic lipid turnover in photoreceptors and retinal pigment epithelium throughout life
The retinal pigment epithelium-photoreceptor interphase is renewed each day in a stunning
display of cellular interdependence. While photoreceptors use photosensitive pigments to …
display of cellular interdependence. While photoreceptors use photosensitive pigments to …
Perspective on AMD pathobiology: a bioenergetic crisis in the RPE
CR Fisher, DA Ferrington - Investigative ophthalmology & …, 2018 - iovs.arvojournals.org
AMD is the leading cause of blindness in developed countries. The dry form of AMD, also
known as atrophic AMD, is characterized by the death of RPE and photoreceptors. Currently …
known as atrophic AMD, is characterized by the death of RPE and photoreceptors. Currently …
Deep-learning-based prediction of late age-related macular degeneration progression
Both genetic and environmental factors influence the etiology of age-related macular
degeneration (AMD), a leading cause of blindness. AMD severity is primarily measured by …
degeneration (AMD), a leading cause of blindness. AMD severity is primarily measured by …
[HTML][HTML] Exosome-mediated delivery of an anti-angiogenic peptide inhibits pathological retinal angiogenesis
X Dong, Y Lei, Z Yu, T Wang, Y Liu, G Han, X Zhang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: Pathological angiogenesis is the hallmark of many vision-threatening
diseases. Anti-VEGF is a primary treatment with substantial beneficial effects. However, such …
diseases. Anti-VEGF is a primary treatment with substantial beneficial effects. However, such …
Restoration of high-sensitivity and adapting vision with a cone opsin
Inherited and age-related retinal degenerative diseases cause progressive loss of rod and
cone photoreceptors, leading to blindness, but spare downstream retinal neurons, which …
cone photoreceptors, leading to blindness, but spare downstream retinal neurons, which …
Gut microbiota influences pathological angiogenesis in obesity‐driven choroidal neovascularization
EMMA Andriessen, AM Wilson, G Mawambo… - EMBO molecular …, 2016 - embopress.org
Age‐related macular degeneration in its neovascular form (NV AMD) is the leading cause of
vision loss among adults above the age of 60. Epidemiological data suggest that in men …
vision loss among adults above the age of 60. Epidemiological data suggest that in men …
Exosomes derived from neural progenitor cells preserve photoreceptors during retinal degeneration by inactivating microglia
B Bian, C Zhao, X He, Y Gong, C Ren… - Journal of …, 2020 - Taylor & Francis
Retinal degeneration (RD) is one of the most common causes of visual impairment and
blindness and is characterized by progressive degeneration of photoreceptors …
blindness and is characterized by progressive degeneration of photoreceptors …