Cationic polymers and their therapeutic potential
SK Samal, M Dash, S Van Vlierberghe… - Chemical Society …, 2012 - pubs.rsc.org
The last decade has witnessed enormous research focused on cationic polymers. Cationic
polymers are the subject of intense research as non-viral gene delivery systems, due to their …
polymers are the subject of intense research as non-viral gene delivery systems, due to their …
RNAi therapeutic and its innovative biotechnological evolution
Y Weng, H ** RES and endosome: challenges for siRNA delivery for cancer therapy
Small interfering RNAs (siRNAs) technology has emerged as a promising potential
treatment for viral, genetic diseases and cancers. Despite the powerful therapeutic potential …
treatment for viral, genetic diseases and cancers. Despite the powerful therapeutic potential …
Polymeric modification and its implication in drug delivery: poly-ε-caprolactone (PCL) as a model polymer
TK Dash, VB Konkimalla - Molecular pharmaceutics, 2012 - ACS Publications
Biodegradable polymers provided the opportunity to explore beyond conventional drug
delivery and turned out to be the focus of current drug delivery. In spite of availability of …
delivery and turned out to be the focus of current drug delivery. In spite of availability of …
Amphiphilic copolymers in biomedical applications: Synthesis routes and property control
The request of new materials, matching strict requirements to be applied in precision and
patient-specific medicine, is pushing for the synthesis of more and more complex block …
patient-specific medicine, is pushing for the synthesis of more and more complex block …
“Triple-punch” strategy for triple negative breast cancer therapy with minimized drug dosage and improved antitumor efficacy
Effective therapeutics against triple negative breast cancer (TNBC), which has no standard-
of-care therapy, needs to be developed urgently. Here we demonstrated a strategy of …
of-care therapy, needs to be developed urgently. Here we demonstrated a strategy of …
Polymeric siRNA gene delivery–transfection efficiency versus cytotoxicity
Within the field of gene therapy, there is a considerable need for the development of non-
viral vectors that are able to compete with the efficiency obtained by viral vectors, while …
viral vectors that are able to compete with the efficiency obtained by viral vectors, while …