Myocardial infarction causes almost 7.3 million deaths each year worldwide. However,
current treatments are more palliative than curative. Presently, cell and protein therapies are …

Acute inflammation is a common dangerous component of pathogenesis of many prevalent
conditions with high morbidity and mortality including sepsis, thrombosis, acute respiratory …

Herein, we describe a method for targeting to and retaining intravenously (IV) injected
nanoparticles at the site of acute myocardial infarction (MI) in a rat model. Enzyme …

The use of pro-angiogenic growth factors in ischemia models has been associated with
limited success in the clinical setting, in part owing to the short lived effect of the injected …

Recent attempts at rebuilding the myocardium using stem cells have yielded disappointing
results. The lack of a supporting vasculature may, in part, explain these disappointing …

Targeting the tumor vasculature and selectively modifying endothelial functions is an
attractive anti-tumor strategy. We prepared polyethyleneglycol modified immunoliposomes …

Both epidemiological and clinical studies have indicated that antioxidants found within fruits,
vegetables, cereals, and teas can decrease oxidative stress and its associated diseases …

The complementary coiled coil forming peptides E4 [(EIAALEK) 4] and K4 [(KIAALKE) 4] are
known to trigger liposomal membrane fusion when tethered to lipid vesicles in the form of …

Since their discovery by Bangham about 50 years ago, liposomes have become promising
tools in drug delivery systems. This has increased the therapeutic index of many drugs, and …

Heart failure (HF) is a clinical syndrome characterized by typical symptoms and signs
caused by a structural and/or functional cardiac abnormality, resulting in a reduced cardiac …