[HTML][HTML] The CCL5/CCR5 axis in cancer progression

D Aldinucci, C Borghese, N Casagrande - Cancers, 2020 - mdpi.com
Tumor cells can “hijack” chemokine networks to support tumor progression. In this context,
the CC chemokine ligand 5/CC chemokine receptor type 5 (CCL5/CCR5) axis is gaining …

[HTML][HTML] Beyond HIV infection: neglected and varied impacts of CCR5 and CCR5Δ32 on viral diseases

JH Ellwanger, B Kulmann-Leal, V de Lima Kaminski… - Virus research, 2020 - Elsevier
The interactions between chemokine receptors and their ligands may affect susceptibility to
infectious diseases as well as their clinical manifestations. These interactions mediate both …

CCR5 is a potential therapeutic target for cancer

H Hemmatazad, MD Berger - Expert opinion on therapeutic targets, 2021 - Taylor & Francis
Introduction Chemokines and their cognate receptors play a major role in modulating
inflammatory responses. Depending on their ligand binding, chemokine receptors can …

p32 promotes melanoma progression and metastasis by targeting EMT markers, Akt/PKB pathway, and tumor microenvironment

S Sinha, SK Singh, N Jangde, R Ray, V Rai - Cell Death & Disease, 2021 - nature.com
Melanoma originates from melanin-producing cells called melanocytes. Melanoma poses a
great risk because of its rapid ability to spread and invade new organs. Cellular metastasis …

CCR5Δ32 in Brazil: Impacts of a European genetic variant on a highly admixed population

B Kulmann-Leal, JH Ellwanger, JAB Chies - Frontiers in Immunology, 2021 - frontiersin.org
The genetic background of Brazilians encompasses Amerindian, African, and European
components as a result of the colonization of an already Amerindian inhabited region by …

Role of C–C chemokine receptor type 5 in pathogenesis of malaria and its severe forms

M Ziliotto, JH Ellwanger… - International Journal …, 2024 - Wiley Online Library
Malaria is a mosquito‐borne disease caused by Plasmodium parasites, responsible for a
significant impact on public health in several tropical and sub‐tropical countries. The …

[HTML][HTML] Time for a New Paradigm in Oncology? Viewpoint of the Radiobiologist

AN Shoutko - Open Journal of Biophysics, 2024 - scirp.org
The current immunooncology artificially ignores the connection with lymphopoiesis, though
is only its derivative. Hematopoietic stem cells (HSC) provide physiological regeneration of …

Investigations into intracellular mechanisms of chemokine signalling in cancer

WY Lai - 2023 - ueaeprints.uea.ac.uk
Aim: Chemokine signalling plays a critical regulatory role in cancer, which was found to be
either tumour-promoting or tumour-suppressive. Although chemokine signalling is a …

Immunophenotypic and molecular profile of cancer stem‐cell markers in ex vivo canine transmissible venereal tumour (CTVT)

F Grandi, HA Miot, RM Rocha… - Veterinary Medicine …, 2022 - Wiley Online Library
Background Several studies have attempted to characterise the origin of canine
transmissible venereal tumour (CTVT). However, the participation of cancer stem cells …

超声参数联合外周血指标诊断儿童淋巴瘤的价值分析.

张倩, 刘百灵, 张琪, **敏 - Journal of Modern Medicine & …, 2024 - search.ebscohost.com
目的探讨超声参数联合外周血指标对儿童淋巴瘤的诊断价值. 方法对2018 年6 月至2020 年10
月该院收治的疑为淋巴瘤的浅表淋巴结肿大123 例患儿进行超声检查, 其中85 …