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Ecology and evolution of Mycobacterium tuberculosis
S Gagneux - Nature Reviews Microbiology, 2018 - nature.com
Tuberculosis (TB) is the number one cause of human death due to an infectious disease.
The causative agents of TB are a group of closely related bacteria known as the …
The causative agents of TB are a group of closely related bacteria known as the …
The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis
Global tuberculosis incidence has declined marginally over the past decade, and
tuberculosis remains out of control in several parts of the world including Africa and Asia …
tuberculosis remains out of control in several parts of the world including Africa and Asia …
Antimicrobial resistance in Mycobacterium tuberculosis: mechanistic and evolutionary perspectives
Antibiotic-resistant Mycobacterium tuberculosis strains are threatening progress in
containing the global tuberculosis epidemic. Mycobacterium tuberculosis is intrinsically …
containing the global tuberculosis epidemic. Mycobacterium tuberculosis is intrinsically …
Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection
Mycobacterium tuberculosis is a leading cause of mortality worldwide and establishes a
long-lived latent infection in a substantial proportion of the human population. Multiple lines …
long-lived latent infection in a substantial proportion of the human population. Multiple lines …
Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages
Generalist and specialist species differ in the breadth of their ecological niches. Little is
known about the niche width of obligate human pathogens. Here we analyzed a global …
known about the niche width of obligate human pathogens. Here we analyzed a global …
Integrating informatics tools and portable sequencing technology for rapid detection of resistance to anti-tuberculous drugs
Background Mycobacterium tuberculosis resistance to anti-tuberculosis drugs is a major
threat to global public health. Whole genome sequencing (WGS) is rapidly gaining traction …
threat to global public health. Whole genome sequencing (WGS) is rapidly gaining traction …
Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance
Multidrug-resistant tuberculosis (MDR-TB), caused by drug-resistant strains of
Mycobacterium tuberculosis, is an increasingly serious problem worldwide. Here we …
Mycobacterium tuberculosis, is an increasingly serious problem worldwide. Here we …
[HTML][HTML] Human tuberculosis and Mycobacterium tuberculosis complex: A review on genetic diversity, pathogenesis and omics approaches in host biomarkers …
Mycobacterium tuberculosis complex (MTBC) refers to a group of mycobacteria
encompassing nine members of closely related species that causes tuberculosis in animals …
encompassing nine members of closely related species that causes tuberculosis in animals …
Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues
Whole genome sequencing (WGS) of Mycobacterium tuberculosis has rapidly progressed
from a research tool to a clinical application for the diagnosis and management of …
from a research tool to a clinical application for the diagnosis and management of …
MTBseq: a comprehensive pipeline for whole genome sequence analysis of Mycobacterium tuberculosis complex isolates
TA Kohl, C Utpatel, V Schleusener, MR De Filippo… - PeerJ, 2018 - peerj.com
Analyzing whole-genome sequencing data of Mycobacterium tuberculosis complex (MTBC)
isolates in a standardized workflow enables both comprehensive antibiotic resistance …
isolates in a standardized workflow enables both comprehensive antibiotic resistance …