Microtubules are cylindrical protein polymers formed from α β-tubulin heterodimers in the
cytoplasm of eukaryotic cells. Microtubule disturbance may cause cell cycle arrest in the …

Background: Cancer is second leading disease after cardiovascular disease. Presently,
Chemotherapy, Radiotherapy and use of chemicals are some treatments available these …

Coordinative polymers (CP) are a subclass of Metal–organic frameworks (MOFs) with
porous microstructures which have been widely synthesized in recent years and applied in …

Effective one‐pot methods were used to synthesize some new alkane‐linked bis (pyrazolo
[5, 1‐b] quinazolines) and bis (9H‐xanthenediones). The first series was produced, in 80 …

A rhodium-catalyzed synthesis of indoloquinazolinone from a readily available hypervalent
iodonium reagent and N-carboxamide indole was developed. The protocol features broad …

Hybrid molecules have attracted attention for their improved biological activity, selectivity
and lesser side effects profile, distinct from their individual components. In the quest for …

A facile and efficient copper-catalyzed domino-double annulation strategy was developed
from easily accessible o-aminobenzamides and 2-iodoisothiocyanates, which affords a …

In our efforts to address the rising incidence of hepatocellular carcinoma (HCC), we have
made a commitment to the synthesis of novel molecules to combat Hep-G2 cells. A facile …

A series of new thiazolo [3, 2-a] pyrimidines different by aryl substituents in 2 and 5 positions
are synthesized and characterized in solution as well as in the crystalline phase using 1H …

Using X-ray diffraction, FT-IR, 1H, 13C NMR, and UV–Vis spectra as well as theoretical DFT
calculations, Ethyl-2-methyl-4-phenyl-3, 4-dihydro-2H-benzo [4, 5] thiazolo-[3, 2-a] …