Retinoblastoma is a rare cancer of the infant retina that is diagnosed in approximately 8,000
children each year worldwide. It forms when both retinoblastoma gene (RB1) alleles are …

Retinoblastoma represents 3% of all childhood cancers, and is the most common intraocular
malignancy of childhood. It is fatal, if untreated. White eye reflex, also known as leukocoria …

Objective To analyze our 5-year experience of intra-arterial chemotherapy (IAC) for
retinoblastoma as primary or secondary therapy. Design Retrospective interventional case …

Retinoblastoma (Rb), the most frequent malignant intraocular tumor in childhood, is caused
by mutations in the retinoblastoma gene (RB1) situated on chromosome 13q14. 2. The …

Targeted retinoblastoma management: when to use intravenous,... : Current Opinion in
Ophthalmology Targeted retinoblastoma management: when to use intravenous, intra-arterial …

Retinoblastoma is one of the most severe ocular diseases, of which current chemotherapy is
limited to the repetitive intravitreal injections of chemotherapeutics. Systemic drug …

Importance Recurrent or persistent vitreous seeds following treatment of retinoblastoma
poses difficult management and often leads to enucleation. Objective To describe the …

Retinoblastoma is the most common primary intraocular malignancy of childhood. It typically
presents with leukocoria or strabismus. In later stages of the disease, the child may exhibit …

Ocular cancers are unique among the diseases of the eye, threatening both vision and life.
In most cases, the diagnosis can be made utilizing a careful clinical history and specialized …

Melphalan is an efficient chemotherapeutic agent that is currently used to treat
retinoblastoma (Rb); however, the inherent risk of immunogenicity and the hazardous …