In recent years, much new data on intestinal alkaline phosphatase (IAP) have been
published, and major breakthroughs have been disclosed. The aim of the present review is …

Cardiovascular calcification (CVC) is associated with increased morbidity and mortality. It
develops in several diseases and locations, such as in the tunica intima in atherosclerosis …

Metal-and additive-free photoredox cyclization of N-arylacrylamides is herein reported that
provides a concise access to the formation of dihydroquinolinones. In this protocol …

Natural products have proved to be a promising source for the development of potential
anticancer drugs. Emodin, a natural compound from Rheum palmatum, is used to treat …

Heterocycles are a class of compounds that have been found to be potent inhibitors of
alkaline phosphatase (AP), an enzyme that plays a critical role in various physiological …

The excelling role of organic chemistry in the medicinal field continues to be one of the main
leads in the drug development process. Particularly, this industry requires organic chemists …

The chemistry of quinolones, representing one of the major classes of nitrogen-containing
heterocyclics, has received more attention and considered one of the promising …

Heterocyclic compounds are indispensable structures that have widespread occurrence in
nature and exhibit fascinating biological and pharmaceutical activities. Particularly …

A simple and practical protocol for the C3–H regioselective halogenation of 4-quinolones by
the action of potassium halide salt and PIFA/PIDA in good to excellent yields was …

To seek the new medicinal potential of sulfadiazine drug, the free amino group of
sulfadiazine was exploited to obtain acyl/aryl thioureas using simple and straightforward …