A comprehensive review of signal peptides: Structure, roles, and applications

H Owji, N Nezafat, M Negahdaripour… - European journal of cell …, 2018 - Elsevier
Signal peptides (SP) are short peptides located in the N-terminal of proteins, carrying
information for protein secretion. They are ubiquitous to all prokaryotes and eukaryotes. SPs …

Glycoinformatics in the artificial intelligence era

D Bojar, F Lisacek - Chemical Reviews, 2022 - ACS Publications
Artificial intelligence (AI) methods have been and are now being increasingly integrated in
prediction software implemented in bioinformatics and its glycoscience branch known as …

SignalP 5.0 improves signal peptide predictions using deep neural networks

JJA Armenteros, KD Tsirigos, CK Sønderby… - Nature …, 2019 - orbit.dtu.dk
Signal peptides (SPs) are short amino acid sequences in the amino terminus of many newly
synthesized proteins that target proteins into, or across, membranes. Bioinformatic tools can …

SignalP 5.0 improves signal peptide predictions using deep neural networks

JJ Almagro Armenteros, KD Tsirigos… - Nature …, 2019 - nature.com
Signal peptides (SPs) are short amino acid sequences in the amino terminus of many newly
synthesized proteins that target proteins into, or across, membranes. Bioinformatic tools can …

Predicting secretory proteins with SignalP

H Nielsen - Protein function prediction: methods and protocols, 2017 - Springer
SignalP is the currently most widely used program for prediction of signal peptides from
amino acid sequences. Proteins with signal peptides are targeted to the secretory pathway …

Penaeidins, a family of antimicrobial peptides from penaeid shrimp (Crustacea, Decapoda)

D Destoumieux, M Munoz, P Bulet… - Cellular and Molecular Life …, 2000 - Springer
The production of antimicrobial peptides represents a first-line host defense mechanism of
innate immunity that is widespread in nature. Only recently such effectors were isolated in …

The in silico human surfaceome

D Bausch-Fluck, U Goldmann… - Proceedings of the …, 2018 - National Acad Sciences
Cell-surface proteins are of great biomedical importance, as demonstrated by the fact that
66% of approved human drugs listed in the DrugBank database target a cell-surface protein …

Evolutionary genomics of the cold-adapted diatom Fragilariopsis cylindrus

T Mock, RP Otillar, J Strauss, M McMullan, P Paajanen… - Nature, 2017 - nature.com
Abstract The Southern Ocean houses a diverse and productive community of organisms,.
Unicellular eukaryotic diatoms are the main primary producers in this environment, where …

SignalP 4.0: discriminating signal peptides from transmembrane regions

TN Petersen, S Brunak, G Von Heijne, H Nielsen - Nature methods, 2011 - nature.com
To the Editor: The secretory signal peptide is a ubiquitous proteinsorting signal that targets
its passenger protein for translocation across the endoplasmic reticulum membrane in …

Extensive sampling of basidiomycete genomes demonstrates inadequacy of the white-rot/brown-rot paradigm for wood decay fungi

R Riley, AA Salamov, DW Brown… - Proceedings of the …, 2014 - National Acad Sciences
Basidiomycota (basidiomycetes) make up 32% of the described fungi and include most
wood-decaying species, as well as pathogens and mutualistic symbionts. Wood-decaying …