Neoadjuvant radiotherapy for rectal cancer management

G Feeney, R Sehgal, M Sheehan… - World journal of …, 2019 - pmc.ncbi.nlm.nih.gov
Thirty per cent of all colorectal tumours develop in the rectum. The location of the rectum
within the bony pelvis and its proximity to vital structures presents significant therapeutic …

Anterior resection syndrome

CLC Bryant, PJ Lunniss, CH Knowles… - The lancet …, 2012 - thelancet.com
Up to 80% of patients with rectal cancer undergo sphincter-preserving surgery. It is widely
accepted that up to 90% of such patients will subsequently have a change in bowel habit …

The American Society of Colon and Rectal Surgeons clinical practice guidelines for the management of rectal cancer

YN You, KM Hardiman, A Bafford, V Poylin… - Diseases of the Colon …, 2020 - journals.lww.com
The American Society of Colon and Rectal Surgeons (ASCRS) is dedicated to ensuring high-
quality patient care by advancing the science, prevention, and management of disorders …

Low anterior resection syndrome score: development and validation of a symptom-based scoring system for bowel dysfunction after low anterior resection for rectal …

KJ Emmertsen, S Laurberg - Annals of surgery, 2012 - journals.lww.com
Objective: The aim of this study was to develop and validate a scoring system for bowel
dysfunction after low anterior resection (LAR) for rectal cancer, on the basis of symptoms …

Impact of bowel dysfunction on quality of life after sphincter-preserving resection for rectal cancer

KJ Emmertsen, S Laurberg, P Jess… - Journal of British …, 2013 - academic.oup.com
Background Bowel dysfunction after sphincter-preserving surgery for rectal cancer is a
common complication, with the potential to affect quality of life (QoL) strongly. The aim of this …

Practice parameters for the management of rectal cancer (revised)

JRT Monson, MR Weiser, WD Buie… - Diseases of the Colon …, 2013 - journals.lww.com
longer distinctly identified, the sacral promontory is generally recognized as the transition
point from a radiographic perspective. Preoperatively, a tumor whose distal margin is seen …

The incidence and risk factors of low anterior resection syndrome (LARS) after sphincter-preserving surgery of rectal cancer: a systematic review and meta-analysis

R Sun, Z Dai, Y Zhang, J Lu, Y Zhang, Y **ao - Supportive Care in Cancer, 2021 - Springer
Background Many patients after sphincter-preserving surgery experienced anorectal
functional disturbances which were known as low anterior resection syndrome (LARS) …

Defining low anterior resection syndrome: a systematic review of the literature

C Keane, C Wells, G O'grady, IP Bissett - Colorectal disease, 2017 - Wiley Online Library
Aim There is increasing awareness of the poor functional outcome suffered by many patients
after sphincter‐preserving rectal resection, termed 'low anterior resection syndrome'(LARS) …

Bowel dysfunction after low anterior resection with and without neoadjuvant therapy for rectal cancer: a population‐based cross‐sectional study

S Bregendahl, KJ Emmertsen, J Lous… - Colorectal …, 2013 - Wiley Online Library
Aim Bowel dysfunction was assessed after low anterior resection with and without
neoadjuvant therapy (NT) for rectal cancer using a novel symptom‐based scoring system …

Development and external validation of a nomogram and online tool to predict bowel dysfunction following restorative rectal cancer resection: the POLARS score

NJ Battersby, G Bouliotis, KJ Emmertsen, T Juul… - Gut, 2018 - gut.bmj.com
Objective Bowel dysfunction is common following a restorative rectal cancer resection, but
symptom severity and the degree of quality of life impairment is highly variable. An …