Mechanobiology emerges at the crossroads of medicine, biology, biophysics and
engineering and describes how the responses of proteins, cells, tissues and organs to …

The physicochemical properties of nanoparticles play critical roles in regulating nano-bio
interactions. Whereas the effects of the size, shape, and surface charge of nanoparticles on …

Nanomedicine has been developed for cancer therapy over several decades, while rapid
clearance from blood circulation by reticuloendothelial system (RES) severely limits …

Modulating nanomedicine mechanical properties for enhanced drug delivery to tumors has
attracted increasing attention in the past few decades. In this tutorial review, we analyze the …

T cell-based adoptive cell therapy (ACT) has emerged as a promising treatment for various
diseases, particularly cancers. Unlike other immunotherapy modalities, ACT involves directly …

The HIV-1 envelope (Env) glycoproteins play an essential role in the virus replication cycle
by mediating the fusion between viral and cellular membranes during the entry process. The …

Particulate carrier systems are promising drug delivery vehicles for subunit vaccination as
they can enhance and direct the type of T cell response. In order to develop vaccines with …

Recent work has identified three distinct classes of viral membrane fusion proteins based on
structural criteria. In addition, there are at least four distinct mechanisms by which viral fusion …

A fundamental understanding of cell-nanomaterial interaction is of essential importance to
nanomedicine and safe applications of nanotechnology. Here we investigate the adhesive …

The advances in micro-and nanofabrication technologies enable the preparation of
increasingly smaller mechanical transducers capable of detecting the forces, motion …