Although some long noncoding (lnc) RNAs are known since the 1950s, the past 25 years
have uncovered myriad lncRNAs with diverse sequences, structures, and functions. The …

Subcellular localization of RNAs has gained attention in recent years as a prevalent
phenomenon that influences numerous cellular processes. This is also evident for the large …

Stimulation of brown adipose tissue (BAT) thermogenesis in humans has emerged as an
attractive target to improve metabolic health. Pharmacological stimulations targeting the β 3 …

The worldwide incidence of obesity and its sequelae, such as type 2 diabetes mellitus, have
reached pandemic levels. Central to the development of these metabolic disorders is …

Deficiency of the epigenome modulator histone deacetylase 3 (HDAC3) in brown adipose
tissue (BAT) impairs the ability of mice to survive in near-freezing temperatures. Here, we …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Brown adipose tissue (BAT) has been encouraged as a potential treatment for obesity and
comorbidities due to its thermogenic activity capacity and contribution to energy expenditure …

As one of novel hallmarks of cancer, lipid metabolic reprogramming has recently been
becoming fascinating and widely studied. Lipid metabolic reprogramming in cancer is …

Long-chain noncoding RNAs (lncRNAs) are RNAs that do not code for proteins, widely
present in eukaryotes. They regulate gene expression at multiple levels through different …

This study reveals a previously uncharacterized mechanism to restrict intestinal
inflammation via a regulatory RNA transcribed from a noncoding genomic locus. We …