Burden of anemia in chronic kidney disease: beyond erythropoietin

RM Hanna, E Streja, K Kalantar-Zadeh - Advances in therapy, 2021 - Springer
Anemia is a frequent comorbidity of chronic kidney disease (CKD) and is associated with a
considerable burden because of decreased patient health-related quality of life and …

Parenteral versus oral iron therapy for adults and children with chronic kidney disease

LO Emma, EM Hodson, I Nistor… - Cochrane Database …, 2019 - cochranelibrary.com
Background The anaemia seen in chronic kidney disease (CKD) may be exacerbated by
iron deficiency. Iron can be provided through different routes, with advantages and …

2017 comprehensive update of the Canadian Cardiovascular Society guidelines for the management of heart failure

JA Ezekowitz, E O'Meara, MA McDonald… - Canadian Journal of …, 2017 - Elsevier
Since the inception of the Canadian Cardiovascular Society heart failure (HF) guidelines in
2006, much has changed in the care for patients with HF. Over the past decade, the HF …

Impact of chronic kidney disease and anemia on health-related quality of life and work productivity: analysis of multinational real-world data

H van Haalen, J Jackson, B Spinowitz, G Milligan… - BMC nephrology, 2020 - Springer
Background Reductions in health-related quality of life (HRQoL) in patients with chronic
kidney disease (CKD) are thought to be exacerbated by the low hemoglobin (Hb) levels that …

Evolving strategies in the treatment of anaemia in chronic kidney disease: the HIF-prolyl hydroxylase inhibitors

F Locatelli, R Minutolo, L De Nicola, L Del Vecchio - Drugs, 2022 - Springer
Chronic kidney disease (CKD) affects approximately 10% of the worldwide population;
anaemia is a frequent complication. Inadequate erythropoietin production and absolute or …

Health-related quality of life in patients with chronic kidney disease

H Hussien, M Apetrii, A Covic - Expert review of …, 2021 - Taylor & Francis
Introduction: In the last three decades, health systems have continued to pay increasing
attention to the quality of life (QOL) due to definitional changes in the concept of health and …

Long-term safety and efficacy of veverimer in patients with metabolic acidosis in chronic kidney disease: a multicentre, randomised, blinded, placebo-controlled, 40 …

DE Wesson, V Mathur, N Tangri, Y Stasiv, D Parsell… - The Lancet, 2019 - thelancet.com
Background Metabolic acidosis, a complication of chronic kidney disease, causes protein
catabolism and bone demineralisation and is associated with adverse kidney outcomes and …

Veverimer versus placebo in patients with metabolic acidosis associated with chronic kidney disease: a multicentre, randomised, double-blind, controlled, phase 3 trial

DE Wesson, V Mathur, N Tangri, Y Stasiv, D Parsell… - The Lancet, 2019 - thelancet.com
Background Patients with advanced chronic kidney disease lose the capacity to fully excrete
endogenous acid, resulting in chronic metabolic acidosis that increases the risk of disease …

[HTML][HTML] Associations of hemoglobin levels with health-related quality of life, physical activity, and clinical outcomes in persons with stage 3-5 nondialysis CKD

J Hoshino, D Muenz, J Zee, N Sukul, E Speyer… - Journal of Renal …, 2020 - Elsevier
Objective Conflicting findings and knowledge gaps exist regarding links between anemia,
physical activity, health-related quality of life (HRQOL), chronic kidney disease (CKD) …

Erythropoietin and nonhematopoietic effects

A Nekoui, G Blaise - The American journal of the medical sciences, 2017 - Elsevier
Erythropoietin (EPO) is the main regulator of red blood cell production. Since the 1990s,
EPO has been used for the treatment of anemia associated with end-stage renal failure and …